Amylyx Pharmaceuticals Ownership | Who Owns Amylyx Pharmaceuticals?

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Amylyx Pharmaceuticals Ownership Summary

Amylyx Pharmaceuticals is owned by 40.52% institutional investors, 7.53% insiders, and 51.95% retail investors. Fmr is the largest institutional shareholder, holding 12.77% of AMLX shares. Vanguard Total Stock Mkt Idx Inv is the top mutual fund, with 2.81% of its assets in Amylyx Pharmaceuticals shares.

AMLX Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Amylyx Pharmaceuticals	40.52%	7.53%	51.95%
Sector	Healthcare Stocks	232.64%	10.66%	-143.30%
Industry	Biotech Stocks	382.13%	10.41%	-292.54%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Fmr	11.38M	12.77%	$154.64M
Perceptive advisors	8.95M	10.04%	$121.66M
Blackrock funding, inc. /de	9.05M	9.70%	$109.38M
Adage capital partners gp	6.82M	7.65%	$92.64M
Tcg crossover management	6.24M	7.00%	$84.85M
Vanguard group	5.80M	6.22%	$70.12M
Saturn v capital management	4.60M	5.17%	$62.58M
Commodore capital lp	4.08M	4.57%	$55.39M
Blackrock	2.67M	3.93%	$5.07M
First light asset management	3.36M	3.76%	$45.61M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Saturn v capital management	4.60M	13.72%	$62.58M
Allostery investments lp	120.12K	9.81%	$769.96K
Great point partners	1.70M	9.53%	$23.10M
Almitas capital	2.12M	6.60%	$28.85M
Acuta capital partners	333.26K	4.68%	$4.53M
First light asset management	3.36M	4.30%	$45.61M
Tcg crossover management	6.24M	4.17%	$84.85M
Boxer capital management	900.00K	3.90%	$12.23M
Ally bridge group (ny)	437.39K	3.62%	$5.94M
Perceptive advisors	8.95M	3.51%	$121.66M

Top Buyers

Holder	Shares	% Assets	Change
Fmr	11.38M	0.01%	8.33M
Commodore capital lp	4.08M	2.70%	4.08M
First light asset management	3.36M	4.30%	3.36M
Blackrock funding, inc. /de	9.05M	0.00%	1.91M
Paradigm biocapital advisors lp	1.90M	0.73%	1.90M

Top Sellers

Holder	Shares	% Assets	Change
Adage capital partners gp	6.82M	0.15%	-1.98M
Blackrock	2.67M	0.00%	-1.80M
Point72 asset management	2.79M	0.06%	-1.75M
Boxer capital	-	-	-1.50M
Farallon capital management	-	-	-1.15M

New Positions

Holder	Shares	% Assets	Change	Value
Commodore capital lp	4.08M	2.70%	4.08M	$55.39M
First light asset management	3.36M	4.30%	3.36M	$45.61M
Paradigm biocapital advisors lp	1.90M	0.73%	1.90M	$25.82M
Eventide asset management	1.51M	0.34%	1.51M	$20.55M
Logos global management lp	1.45M	1.77%	1.45M	$19.71M

Sold Out

Holder	Change
Nelson, van denburg & campbell wealth management group	-10.00
Kelly financial services	-33.00
Skopos labs	-42.00
Salem investment counselors	-55.00
Rise advisors	-64.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Dec 31, 2025	114	-35.23%	37,817,895	-65.53%	40	0.27%	65	-38.10%	25	-46.81%
Sep 30, 2025	170	34.92%	109,563,434	39.61%	122	1.59%	101	46.38%	46	43.75%
Jun 30, 2025	131	-2.96%	81,652,437	17.21%	91	1.39%	70	-12.50%	35	12.90%
Mar 31, 2025	137	3.79%	73,635,543	47.89%	85	1.61%	82	24.24%	30	-26.83%
Dec 31, 2024	130	12.07%	49,788,210	14.69%	73	1.80%	65	18.18%	40	14.29%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard Total Stock Mkt Idx Inv	3.10M	2.81%	-
Fidelity Advisor Biotechnology I	2.43M	2.20%	-
iShares Russell 2000 ETF	2.21M	2.00%	-18.05K
Fidelity Small Cap Growth	2.12M	1.91%	-
Eventide Healthcare & Life Sciences I	1.51M	1.37%	-
Fidelity Select Health Care	1.42M	1.28%	-
Xtrackers S&P 500 Swap ETF 1C	1.24M	1.13%	-9.15K
Fidelity Select Biotechnology	1.22M	1.10%	-112.30K
Strategic Advisers Fidelity US TtlStk	1.14M	1.03%	60.00K
Fidelity Stock Selector Small Cap	1.09M	0.98%	-

Recent Insider Transactions

Date	Name	Role	Activity	Value
Mar 02, 2026	Klee Justin B.	Co-Chief Executive Officer	Sell	$423.76K
Mar 02, 2026	Cohen Joshua B	Co-Chief Executive Officer	Sell	$424.12K
Mar 02, 2026	Bedrosian Camille L	Chief Medical Officer	Sell	$94.21K
Mar 02, 2026	FRATES JAMES M	Chief Financial Officer	Sell	$114.85K
Mar 02, 2026	Mazzariello Gina	Chief Legal Officer	Sell	$99.38K

Insider Transactions Trends

Date	Buy	Sell
2026 Q1	-	17
2025 Q4	1	1
2025 Q3	-	9
2025 Q2	-	-
2025 Q1	1	14

AMLX Ownership FAQ

Who Owns Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals shareholders are primarily institutional investors at 40.52%, followed by 7.53% insiders and 51.95% retail investors. The average institutional ownership in Amylyx Pharmaceuticals's industry, Biotech Stocks , is 382.13%, which Amylyx Pharmaceuticals falls below.

Who owns the most shares of Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals’s largest shareholders are Fmr (11.38M shares, 12.77%), Perceptive advisors (8.95M shares, 10.04%), and Blackrock funding, inc. /de (9.05M shares, 9.70%). Together, they hold 32.51% of Amylyx Pharmaceuticals’s total shares outstanding.

Does Blackrock own Amylyx Pharmaceuticals?

Yes, BlackRock owns 3.93% of Amylyx Pharmaceuticals, totaling 2.67M shares as of Jun 2024. This represents 0.00% of BlackRock's total assets, with a market value of 5.07M$. In the last quarter, BlackRock decreased its holdings by -1.805M shares, a -40.34% change.

Who is Amylyx Pharmaceuticals’s biggest shareholder by percentage of total assets invested?

Saturn v capital management is Amylyx Pharmaceuticals’s biggest shareholder by percentage of total assets invested, with 13.72% of its assets in 4.6M Amylyx Pharmaceuticals shares, valued at 62.58M$.

Who is the top mutual fund holder of Amylyx Pharmaceuticals shares?

Vanguard Total Stock Mkt Idx Inv is the top mutual fund holder of Amylyx Pharmaceuticals shares, with 2.81% of its total shares outstanding invested in 3.1M Amylyx Pharmaceuticals shares.

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