Denali Therapeutics Ownership | Who Owns Denali Therapeutics?

Denali Therapeutics Ownership Summary

Denali Therapeutics is owned by 80.04% institutional investors, 9.83% insiders, and 10.13% retail investors. Blackrock is the largest institutional shareholder, holding 8.82% of DNLI shares. Scottish Mortgage Ord is the top mutual fund, with 4.48% of its assets in Denali Therapeutics shares.

DNLI Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Denali Therapeutics	80.04%	9.83%	10.13%
Sector	Healthcare Stocks	479.67%	11.03%	-390.70%
Industry	Biotech Stocks	295.80%	10.97%	-206.77%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Blackrock	13.17M	8.82%	$305.91M
Baillie gifford	12.31M	7.27%	$250.96M
Vanguard group	12.02M	7.09%	$244.99M
Blackrock funding, inc. /de	12.05M	7.03%	$168.63M
Wellington management group llp	9.85M	5.81%	$200.70M
Fmr	8.02M	4.73%	$163.44M
Temasek (private)	5.36M	3.12%	$74.93M
Capital research global investors	4.75M	2.77%	$66.46M
State street	4.54M	2.68%	$92.63M
Crestline management, lp	3.86M	2.25%	$54.01B

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Crestline management, lp	3.86M	86.33%	$54.01B
Stempoint capital lp	707.91K	3.18%	$9.90M
Casdin capital	890.00K	1.13%	$12.45M
Palo alto investors lp	239.81K	0.71%	$3.35M
Pier capital	314.80K	0.67%	$4.40M
Dafna capital management	168.50K	0.65%	$2.36M
Siren	821.51K	0.59%	$11.49M
Yiheng capital management	469.98K	0.59%	$6.58M
Clarius group	410.00K	0.57%	$8.36M
Camber capital management lp	400.00K	0.53%	$5.60M

Top Buyers

Holder	Shares	% Assets	Change
T. rowe price investment management	3.25M	0.03%	3.25M
Point72 asset management	2.21M	0.06%	2.21M
Norges bank	1.07M	0.00%	1.07M
Blackrock	13.17M	0.01%	974.71K
Vanguard group	12.02M	0.00%	844.00K

Top Sellers

Holder	Shares	% Assets	Change
Blackrock funding, inc. /de	12.05M	0.00%	-1.78M
Flagship pioneering	-	-	-1.36M
Gilder gagnon howe	-	-	-1.17M
Baillie gifford	12.31M	0.19%	-1.03M
Wellington management group llp	9.85M	0.04%	-879.50K

New Positions

Holder	Shares	% Assets	Change	Value
T. rowe price investment management	3.25M	0.03%	3.25M	$45.42M
Norges bank	1.07M	0.00%	1.07M	$21.72M
Masters capital management	600.00K	0.33%	600.00K	$8.39M
Edgestream partners	342.92K	0.13%	342.92K	$4.80M
Segall bryant & hamill	289.07K	0.08%	289.07K	$5.89M

Sold Out

Holder	Change
Ifp advisors	-1.00
Dinuzzo private wealth	-2.00
Toronto dominion bank	-2.00
Global financial private client	-5.00
Svb wealth	-11.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Jun 30, 2025	230	4.07%	137,233,427	3.48%	80	1.33%	122	14.02%	66	-17.50%
Mar 31, 2025	220	-3.51%	132,840,276	3.83%	77	1.36%	108	-14.96%	80	35.59%
Dec 31, 2024	227	2.71%	127,936,943	1.24%	75	1.36%	125	8.70%	60	3.45%
Sep 30, 2024	220	6.80%	126,341,996	5.65%	74	1.49%	116	1.75%	57	-5.00%
Jun 30, 2024	204	-3.77%	119,583,732	2.39%	80	1.11%	113	2.73%	59	-13.24%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Scottish Mortgage Ord	6.53M	4.48%	-
Vanguard Health Care Inv	4.40M	3.03%	-5.17M
Vanguard Total Stock Mkt Idx Inv	3.81M	2.62%	25.86K
Vanguard US Total Market Shares ETF	3.33M	2.29%	-161.11K
American Funds SMALLCAP World A	3.21M	2.21%	-16.49K
Baillie Gifford US Equity Growth	3.17M	2.20%	-205.95K
iShares Russell 2000 ETF	3.11M	2.14%	-59.12K
Vanguard US Growth Investor	3.03M	2.08%	-
Vanguard Small Cap Index	2.84M	1.95%	-62.66K
T. Rowe Price Health Sciences	2.50M	1.72%	115.42K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Aug 12, 2025	Schuth Alexander O.	COFO and Secretary	Sell	$39.88K
Aug 12, 2025	Ho Carole	Chief Medical Officer	Sell	$39.88K
Aug 13, 2025	Ho Carole	Chief Medical Officer	Sell	$11.80K
Jul 09, 2025	Watts Ryan J.	President and CEO	Sell	$7.43M
Jan 06, 2025	Ho Carole	Chief Medical Officer	Sell	$247.80K

Insider Transactions Trends

Date	Buy	Sell
2025 Q3	-	4
2025 Q2	-	-
2025 Q1	-	8
2024 Q4	-	9
2024 Q3	-	18

DNLI Ownership FAQ

Who Owns Denali Therapeutics?

Denali Therapeutics shareholders are primarily institutional investors at 80.04%, followed by 9.83% insiders and 10.13% retail investors. The average institutional ownership in Denali Therapeutics's industry, Biotech Stocks , is 295.80%, which Denali Therapeutics falls below.

Who owns the most shares of Denali Therapeutics?

Denali Therapeutics’s largest shareholders are Blackrock (13.17M shares, 8.82%), Baillie gifford (12.31M shares, 7.27%), and Vanguard group (12.02M shares, 7.09%). Together, they hold 23.18% of Denali Therapeutics’s total shares outstanding.

Does Blackrock own Denali Therapeutics?

Yes, BlackRock owns 8.82% of Denali Therapeutics, totaling 13.17M shares as of Jun 2024. This represents 0.01% of BlackRock's total assets, with a market value of 305.91M$. In the last quarter, BlackRock increased its holdings by 974.71K shares, a 7.99% change.

Who is Denali Therapeutics’s biggest shareholder by percentage of total assets invested?

Crestline management, lp is Denali Therapeutics’s biggest shareholder by percentage of total assets invested, with 86.33% of its assets in 3.86M Denali Therapeutics shares, valued at 54.01B$.

Who is the top mutual fund holder of Denali Therapeutics shares?

Scottish Mortgage Ord is the top mutual fund holder of Denali Therapeutics shares, with 4.48% of its total shares outstanding invested in 6.53M Denali Therapeutics shares.

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