Ionis Pharmaceuticals Ownership | Who Owns Ionis Pharmaceuticals?

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Ionis Pharmaceuticals Ownership Summary

Ionis Pharmaceuticals is owned by 106.57% institutional investors, 0.78% insiders. Fmr is the largest institutional shareholder, holding 15.27% of IONS shares. Fidelity Growth Compy Commingled Pl S is the top mutual fund, with 6.84% of its assets in Ionis Pharmaceuticals shares.

IONS Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Ionis Pharmaceuticals	106.57%	0.78%	-7.35%
Sector	Healthcare Stocks	487.91%	11.08%	-398.99%
Industry	Biotech Stocks	307.10%	11.11%	-218.21%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Fmr	22.69M	15.27%	$793.22M
Vanguard group	16.47M	11.09%	$575.88M
T. rowe price investment management	16.05M	10.08%	$634.09M
Capital world investors	12.54M	7.88%	$495.46M
Blackrock	10.32M	7.09%	$491.90M
Blackrock funding, inc. /de	10.90M	6.85%	$430.54M
Wellington management group llp	8.67M	5.84%	$303.18M
Bellevue group	7.85M	4.93%	$310.28M
Deep track capital, lp	4.89M	3.07%	$193.26M
State street	4.19M	2.88%	$199.72M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Great point partners	500.00K	12.84%	$19.75M
Tweedy, browne	2.89M	10.60%	$114.26M
Bellevue group	7.85M	6.84%	$310.28M
Deep track capital, lp	4.89M	6.20%	$193.26M
Superstring capital management lp	98.27K	4.60%	$3.88M
Sector gamma as	285.84K	3.69%	$11.29M
Capricorn fund managers	162.80K	3.58%	$10.65M
Orion investment	217.37K	3.04%	$8.59M
Exome asset management	121.12K	3.02%	$4.79M
Sicart associates	164.32K	2.91%	$10.75M

Top Buyers

Holder	Shares	% Assets	Change
Adage capital partners gp	3.80M	0.25%	2.72M
Ubs group	1.92M	0.01%	1.75M
Norges bank	1.71M	0.01%	1.71M
Vanguard group	16.47M	0.01%	1.42M
Polar capital	1.00M	0.21%	1.00M

Top Sellers

Holder	Shares	% Assets	Change
Orbimed advisors	-	-	-2.54M
Clearbridge investments	-	-	-1.62M
Logos global management lp	-	-	-750.00K
Camber capital management lp	-	-	-725.00K
Man group	8.31K	0.00%	-587.95K

New Positions

Holder	Shares	% Assets	Change	Value
Norges bank	1.71M	0.01%	1.71M	$59.95M
Polar capital	1.00M	0.21%	1.00M	$39.51M
Balyasny asset management	768.65K	0.05%	768.65K	$30.37M
Massachusetts financial services co /ma/	519.18K	0.01%	519.18K	$20.51M
Great lakes advisors	399.65K	0.13%	399.65K	$15.79M

Sold Out

Holder	Change
Activest wealth management	-1.00
Mv capital management	-3.00
Hexagon capital partners	-9.00
Voisard asset management group	-10.00
Central trust	-15.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Jun 30, 2025	379	3.55%	169,594,655	1.94%	106	0.97%	201	28.85%	108	-14.29%
Mar 31, 2025	15	-96.08%	14,001,670	-91.30%	8	0.08%	6	-96.65%	6	-94.92%
Dec 31, 2024	235	-38.48%	100,254,792	-35.75%	67	0.61%	111	-39.34%	73	-31.78%
Sep 30, 2024	378	0.27%	156,005,896	8.92%	104	1.08%	182	3.41%	106	-17.83%
Jun 30, 2024	375	-2.60%	143,227,487	1.66%	98	1.02%	176	2.92%	127	0.79%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Fidelity Growth Compy Commingled Pl S	10.91M	6.84%	14.25K
Fidelity Growth Compy Commingled Pl O	9.71M	6.16%	90.97K
BB Biotech AG Ord	7.85M	4.97%	-
Fidelity Growth Company Fund	7.70M	4.83%	-46.11K
T. Rowe Price US Mid-Cap Growth Equity	5.99M	3.77%	300.20K
T. Rowe Price Mid-Cap Growth	5.98M	3.75%	-11.00K
Vanguard Total Stock Mkt Idx Inv	4.77M	2.99%	-99.81K
American Funds SMALLCAP World A	4.57M	2.87%	108.08K
Vanguard US Total Market Shares ETF	4.50M	2.83%	256.36K
Vanguard Health Care Inv	3.99M	2.50%	-1.74M

Recent Insider Transactions

Date	Name	Role	Activity	Value
Oct 16, 2025	Swayze Eric	EVP Research	Sell	$3.90K
Oct 15, 2025	PARSHALL B LYNNE	-	Sell	$358.72K
Oct 16, 2025	Devers Shannon L.	EVP, Chief Human Resources Ofc	Sell	$92.98K
Oct 15, 2025	Devers Shannon L.	EVP, Chief Human Resources Ofc	Sell	$437.65K
Oct 15, 2025	Birchler Brian	EVP, Corp and Development Ops	Sell	$897.40K

Insider Transactions Trends

Date	Buy	Sell
2025 Q4	-	16
2025 Q3	-	40
2025 Q2	1	3
2025 Q1	-	23
2024 Q4	2	4

IONS Ownership FAQ

Who Owns Ionis Pharmaceuticals?

Ionis Pharmaceuticals shareholders are primarily institutional investors at 106.57%, followed by 0.78% insiders and -7.35% retail investors. The average institutional ownership in Ionis Pharmaceuticals's industry, Biotech Stocks , is 307.10%, which Ionis Pharmaceuticals falls below.

Who owns the most shares of Ionis Pharmaceuticals?

Ionis Pharmaceuticals’s largest shareholders are Fmr (22.69M shares, 15.27%), Vanguard group (16.47M shares, 11.09%), and T. rowe price investment management (16.05M shares, 10.08%). Together, they hold 36.44% of Ionis Pharmaceuticals’s total shares outstanding.

Does Blackrock own Ionis Pharmaceuticals?

Yes, BlackRock owns 7.09% of Ionis Pharmaceuticals, totaling 10.32M shares as of Jun 2024. This represents 0.01% of BlackRock's total assets, with a market value of 491.9M$. In the last quarter, BlackRock increased its holdings by 549.14K shares, a 5.62% change.

Who is Ionis Pharmaceuticals’s biggest shareholder by percentage of total assets invested?

Great point partners is Ionis Pharmaceuticals’s biggest shareholder by percentage of total assets invested, with 12.84% of its assets in 500K Ionis Pharmaceuticals shares, valued at 19.76M$.

Who is the top mutual fund holder of Ionis Pharmaceuticals shares?

Fidelity Growth Compy Commingled Pl S is the top mutual fund holder of Ionis Pharmaceuticals shares, with 6.84% of its total shares outstanding invested in 10.91M Ionis Pharmaceuticals shares.

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