Karyopharm Therapeutics Ownership | Who Owns Karyopharm Therapeutics?
Karyopharm Therapeutics Ownership Summary
Karyopharm Therapeutics is owned by 50.86% institutional investors, 6.29% insiders, and 42.84% retail investors. T. rowe price investment management is the largest institutional shareholder, holding 8.45% of KPTI shares. T. Rowe Price Small-Cap Value is the top mutual fund, with 5.13% of its assets in Karyopharm Therapeutics shares.
KPTI Ownership Benchmark
| Type | Name | % Inst | % Insiders | % Retail |
|---|---|---|---|---|
| Stock | Karyopharm Therapeutics | 50.86% | 6.29% | 42.84% |
| Sector | Healthcare Stocks | 487.91% | 11.08% | -398.99% |
| Industry | Biotech Stocks | 306.69% | 11.10% | -217.79% |
Institutional Shareholders
Top Institutional Shareholders by Total Shares
| Holder | Shares | % Holding | Value |
|---|---|---|---|
| T. rowe price investment management | 728.77K | 8.45% | $3.14M |
| Adage capital partners gp | 421.32K | 4.89% | $1.82M |
| Blackrock | 4.17M | 3.61% | $3.62M |
| Eversept partners, lp | 257.15K | 2.98% | $1.11M |
| Blackrock funding, inc. /de | 236.64K | 2.75% | $1.02M |
| Palo alto investors lp | 187.91K | 2.18% | $809.90K |
| Avidity partners management lp | 134.57K | 1.56% | $579.98K |
| Marshall wace, llp | 128.45K | 1.49% | $553.62K |
| C worldwide group | 100.00K | 1.16% | $654.00K |
| Renaissance | 1.20M | 0.96% | $813.31K |
Top Institutional Shareholders by % of Total Assets
| Holder | Shares | % Assets | Value |
|---|---|---|---|
| Birchview capital, lp | 419.83K | 0.23% | $283.93K |
| Palo alto investors lp | 187.91K | 0.17% | $809.90K |
| Avidity partners management lp | 134.57K | 0.12% | $579.98K |
| Eversept partners, lp | 257.15K | 0.10% | $1.11M |
| Silverback asset management | 70.00K | 0.04% | $301.70K |
| Ikarian capital | 27.26K | 0.02% | $117.48K |
| C worldwide group | 100.00K | 0.01% | $654.00K |
| Adage capital partners gp | 421.32K | 0.00% | $1.82M |
| Xtx topco | 13.06K | 0.00% | $56.27K |
| T. rowe price investment management | 728.77K | 0.00% | $3.14M |
Top Buyers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| T. rowe price investment management | 728.77K | 0.00% | 589.12K |
| Susquehanna group, llp | 664.14K | 0.00% | 361.60K |
| Palo alto investors lp | 187.91K | 0.17% | 187.91K |
| Alyeska investment group | 144.51K | 0.00% | 144.51K |
| Bank of america corp /de/ | 298.69K | - | 140.77K |
Top Sellers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Vanguard group | - | - | -7.65M |
| Blackrock | 4.17M | 0.00% | -5.28M |
| Exome asset management | - | - | -2.00M |
| State street | 453.81K | - | -1.83M |
| Gsa capital partners llp | - | - | -1.60M |
New Positions
| Holder | Shares | % Assets | Change | Value |
|---|---|---|---|---|
| Palo alto investors lp | 187.91K | 0.17% | 187.91K | $809.90K |
| Belvedere trading | 14.56K | 0.00% | 14.56K | $95.24K |
| Xtx topco | 13.06K | 0.00% | 13.06K | $56.27K |
| Baird financial group | 10.53K | 0.00% | 10.53K | $45.39K |
| Rise advisors | 131.00 | 0.00% | 131.00 | $857.00 |
Sold Out
| Holder | Change |
|---|---|
| Zurcher kantonalbank (zurich cantonalbank) | -6.00 |
| Farther finance advisors | -13.00 |
| Nelson, van denburg & campbell wealth management group | -22.00 |
| Financial gravity asset management | -50.00 |
| Nisa investment advisors | -50.00 |
Institutional Ownership Trends
| Date | Holdings | Change % | Shares | Change % | Ownership | Change % | Increased Position | Change % | Decreased Position | Change % |
|---|---|---|---|---|---|---|---|---|---|---|
| Jun 30, 2025 | 52 | 4.00% | 4,384,528 | -15.32% | 50 | 281.78% | 27 | 575.00% | 7 | -83.33% |
| Mar 31, 2025 | 51 | -45.74% | 5,312,129 | -91.28% | 4 | 0.17% | 4 | -88.89% | 43 | 86.96% |
| Dec 31, 2024 | 92 | -4.17% | 60,468,438 | 1.78% | 48 | 2.14% | 34 | 13.33% | 24 | -22.58% |
| Sep 30, 2024 | 96 | -20.00% | 59,409,677 | -12.02% | 47 | 1.39% | 31 | -41.51% | 31 | -6.06% |
| Jun 30, 2024 | 120 | - | 67,526,761 | -9.69% | 58 | 1.36% | 53 | -7.02% | 33 | 6.45% |
Top Mutual Funds Shareholders
| Holder | Shares | % Holding | Change |
|---|---|---|---|
| T. Rowe Price Small-Cap Value | 445.26K | 5.13% | -1.02K |
| T. Rowe Price U.S. SC Value Eq Tr-D | 263.68K | 3.05% | 213.59K |
| Vanguard US Total Market Shares ETF | 3.42M | 2.71% | -1.00 |
| Vanguard Total Stock Mkt Idx Inv | 223.22K | 2.58% | -4.88K |
| Vanguard Explorer Inv | 133.88K | 1.55% | - |
| C WorldWide Healthcare Select 1A | 100.00K | 1.16% | - |
| Vanguard Institutional Extnd Mkt Idx Tr | 80.72K | 0.93% | -36.78K |
| AlphaCentric LifeSci Healthcare I | 1.13M | 0.90% | - |
| AlphaCentric Life Sciences & Hlthcare I | 1.13M | 0.89% | - |
| Kennedy Micro Cap | 1.03M | 0.81% | -22.77K |
Recent Insider Transactions
| Date | Name | Role | Activity | Value |
|---|---|---|---|---|
| Oct 01, 2025 | Abate Kristin | Chief Accounting Officer | Sell | $2.28K |
| Sep 15, 2025 | Paulson Richard A. | President and CEO | Sell | $8.08K |
| Sep 15, 2025 | Mano Michael | SVP, General Counsel&Secretary | Sell | $1.50K |
| Sep 15, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | $2.58K |
| Sep 15, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | $2.62K |
Insider Transactions Trends
| Date | Buy | Sell |
|---|---|---|
| 2025 Q4 | - | 1 |
| 2025 Q3 | - | 9 |
| 2025 Q2 | - | 3 |
| 2025 Q1 | - | 4 |
| 2024 Q4 | - | 3 |
KPTI Ownership FAQ
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