Karyopharm Therapeutics Ownership | Who Owns Karyopharm Therapeutics?
Karyopharm Therapeutics Ownership Summary
Karyopharm Therapeutics is owned by 81.50% institutional investors, 4.46% insiders, and 14.04% retail investors. Ra capital management is the largest institutional shareholder, holding 17.53% of KPTI shares. Vanguard Morn Total Stk Mkt Idx Investor is the top mutual fund, with 2.99% of its assets in Karyopharm Therapeutics shares.
KPTI Ownership Benchmark
| Type | Name | % Inst | % Insiders | % Retail |
|---|---|---|---|---|
| Stock | Karyopharm Therapeutics | 81.50% | 4.46% | 14.04% |
| Sector | Healthcare Stocks | 50.59% | 12.40% | 37.01% |
| Industry | Biotech Stocks | 49.10% | 12.14% | 38.76% |
Institutional Shareholders
Top Institutional Shareholders by Total Shares
| Holder | Shares | % Holding | Value |
|---|---|---|---|
| Ra capital management | 1.92M | 17.53% | $10.68M |
| Adage capital partners gp | 1.81M | 16.52% | $10.06M |
| T. rowe price investment management | 1.54M | 14.10% | $8.59M |
| Goldman sachs group | 947.58K | 8.67% | $5.28M |
| Catalio capital management, lp | 897.71K | 8.21% | $5.00M |
| Vanguard group | 559.62K | 6.46% | $4.12M |
| Affinity asset advisors | 500.00K | 4.57% | $2.79M |
| Avidity partners management lp | 463.74K | 4.24% | $3.85M |
| Soleus capital management | 440.00K | 4.02% | $2.45M |
| Millennium management | 420.57K | 3.85% | $2.34M |
Top Institutional Shareholders by % of Total Assets
| Holder | Shares | % Assets | Value |
|---|---|---|---|
| Catalio capital management, lp | 897.71K | 1.04% | $5.00M |
| Avidity partners management lp | 463.74K | 0.87% | $3.85M |
| Acorn capital advisors | 287.83K | 0.46% | $1.60M |
| Birchview capital, lp | 419.83K | 0.23% | $283.93K |
| Boxer capital management | 302.54K | 0.22% | $1.69M |
| Affinity asset advisors | 500.00K | 0.14% | $2.79M |
| Ra capital management | 1.92M | 0.11% | $10.68M |
| Soleus capital management | 440.00K | 0.10% | $2.45M |
| Eversept partners, lp | 276.17K | 0.08% | $1.54M |
| Silverback asset management | 65.00K | 0.05% | $362.05K |
Top Buyers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Ra capital management | 1.92M | 0.11% | 1.92M |
| Adage capital partners gp | 1.81M | 0.02% | 1.39M |
| Goldman sachs group | 947.58K | 0.00% | 947.58K |
| Catalio capital management, lp | 897.71K | 1.04% | 754.73K |
| Millennium management | 420.57K | 0.00% | 420.57K |
Top Sellers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Blackrock | 4.17M | 0.00% | -5.28M |
| Commodore capital lp | - | - | -1.95M |
| Deutsche bank ag\ | - | - | -1.27M |
| Kennedy capital management | - | - | -1.20M |
| Alphacentric advisors | - | - | -1.13M |
New Positions
| Holder | Shares | % Assets | Change | Value |
|---|---|---|---|---|
| Ra capital management | 1.92M | 0.11% | 1.92M | $10.68M |
| Millennium management | 420.57K | 0.00% | 420.57K | $2.34M |
| Acorn capital advisors | 287.83K | 0.46% | 287.83K | $1.60M |
| Eversept partners, lp | 276.17K | 0.08% | 276.17K | $1.54M |
| Brevan howard capital management lp | 212.37K | 0.01% | 212.37K | $1.18M |
Sold Out
| Holder | Change |
|---|---|
| Pittenger & anderson | -3.00 |
| Zurcher kantonalbank (zurich cantonalbank) | -6.00 |
| Advisory services network | -12.00 |
| Farther finance advisors | -13.00 |
| Nelson, van denburg & campbell wealth management group | -22.00 |
Institutional Ownership Trends
| Date | Holdings | Change % | Shares | Change % | Ownership | Change % | Increased Position | Change % | Decreased Position | Change % |
|---|---|---|---|---|---|---|---|---|---|---|
| Mar 31, 2026 | 65 | -14.47% | 8,911,554 | -5.86% | 81 | 2.94% | 40 | -13.04% | 6 | - |
| Dec 31, 2025 | 12 | -79.31% | 752,172 | -74.49% | 8 | 0.74% | 5 | -72.22% | - | -100.00% |
| Sep 30, 2025 | 18 | -62.50% | 552,924 | -86.33% | 6 | 0.29% | 5 | -79.17% | 3 | -50.00% |
| Jun 30, 2025 | 52 | 4.00% | 4,384,528 | -15.32% | 50 | 281.78% | 27 | 575.00% | 7 | -83.33% |
| Mar 31, 2025 | 51 | -45.74% | 5,312,129 | -91.28% | 4 | 0.17% | 4 | -88.89% | 43 | 86.96% |
Top Mutual Funds Shareholders
| Holder | Shares | % Holding | Change |
|---|---|---|---|
| Vanguard Morn Total Stk Mkt Idx Investor | 677.73K | 2.99% | 168.60K |
| Vanguard Total Stock Mkt Idx Inv | 677.73K | 2.99% | 168.60K |
| Vanguard MStar Total Stk Mkt Idx Invest | 677.73K | 2.99% | - |
| Vanguard US Total Market Shares ETF | 3.42M | 2.71% | -1.00 |
| iShares Russell 2000 ETF | 479.64K | 2.12% | -8.54K |
| T. Rowe Price Small-Cap Value | 435.07K | 1.92% | -100.40K |
| Vanguard Explorer Inv | 133.88K | 1.55% | - |
| T. Rowe Price U.S. SC Value Eq Tr-D | 312.41K | 1.38% | -298.64K |
| Vanguard Institutional Extnd Mkt Idx Tr | 263.08K | 1.16% | - |
| AlphaCentric LifeSci Healthcare I | 1.13M | 0.90% | - |
Recent Insider Transactions
| Date | Name | Role | Activity | Value |
|---|---|---|---|---|
| Jul 28, 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | $1.34K |
| May 14, 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | $3.83K |
| May 14, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | $3.88K |
| May 14, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | $3.08K |
| May 14, 2026 | Abate Kristin | Chief Accounting Officer | Sell | $503.50 |
Insider Transactions Trends
| Date | Buy | Sell |
|---|---|---|
| 2026 Q3 | - | 1 |
| 2026 Q2 | - | 7 |
| 2026 Q1 | - | 9 |
| 2025 Q4 | - | 1 |
| 2025 Q3 | - | 9 |
KPTI Ownership FAQ
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