Karyopharm Therapeutics Ownership | Who Owns Karyopharm Therapeutics?


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Karyopharm Therapeutics Ownership Summary


Karyopharm Therapeutics is owned by 50.86% institutional investors, 6.29% insiders, and 42.84% retail investors. T. rowe price investment management is the largest institutional shareholder, holding 8.45% of KPTI shares. T. Rowe Price Small-Cap Value is the top mutual fund, with 5.17% of its assets in Karyopharm Therapeutics shares.

KPTI Ownership Benchmark


TypeName% Inst% Insiders% Retail
StockKaryopharm Therapeutics50.86%6.29%42.84%
SectorHealthcare Stocks 488.17%11.08%-399.26%
IndustryBiotech Stocks 307.00%11.11%-218.12%

Institutional Shareholders


Top Institutional Shareholders by Total Shares

HolderShares% HoldingValue
T. rowe price investment management728.77K8.45%$3.14M
Adage capital partners gp421.32K4.89%$1.82M
Blackrock4.17M3.61%$3.62M
Eversept partners, lp257.15K2.98%$1.11M
Blackrock funding, inc. /de236.64K2.75%$1.02M
Palo alto investors lp187.91K2.18%$809.90K
Avidity partners management lp134.57K1.56%$579.98K
Marshall wace, llp128.45K1.49%$553.62K
Renaissance1.20M0.96%$813.31K
Silverback asset management70.00K0.81%$301.70K

Top Institutional Shareholders by % of Total Assets

HolderShares% AssetsValue
Birchview capital, lp419.83K0.23%$283.93K
Palo alto investors lp187.91K0.17%$809.90K
Avidity partners management lp134.57K0.12%$579.98K
Eversept partners, lp257.15K0.10%$1.11M
Silverback asset management70.00K0.04%$301.70K
Ikarian capital27.26K0.02%$117.48K
Adage capital partners gp421.32K0.00%$1.82M
Xtx topco13.06K0.00%$56.27K
T. rowe price investment management728.77K0.00%$3.14M
Renaissance1.20M0.00%$813.31K

Top Buyers

HolderShares% AssetsChange
T. rowe price investment management728.77K0.00%589.12K
Susquehanna group, llp664.14K0.00%361.60K
Palo alto investors lp187.91K0.17%187.91K
Alyeska investment group144.51K0.00%144.51K
Bank of america corp /de/298.69K-140.77K

Top Sellers

HolderShares% AssetsChange
Vanguard group---7.65M
Blackrock4.17M0.00%-5.28M
Exome asset management---2.00M
State street453.81K--1.83M
Gsa capital partners llp---1.60M

New Positions

HolderShares% AssetsChangeValue
Palo alto investors lp187.91K0.17%187.91K$809.90K
Xtx topco13.06K0.00%13.06K$56.27K
Baird financial group10.53K0.00%10.53K$45.39K
Raymond james financial90.00-90.00$388.00
Fortitude family office81.000.00%81.00$349.00

Sold Out

HolderChange
Zurcher kantonalbank (zurich cantonalbank)-6.00
Farther finance advisors-13.00
Nelson, van denburg & campbell wealth management group-22.00
Nisa investment advisors-50.00
Financial gravity asset management-50.00

Institutional Ownership Trends


DateHoldingsChange %SharesChange %OwnershipChange %Increased PositionChange %Decreased PositionChange %
Jun 30, 2025524.00%4,384,528-15.32%50281.78%27575.00%7-83.33%
Mar 31, 202551-45.74%5,312,129-91.28%40.17%4-88.89%4386.96%
Dec 31, 202492-4.17%60,468,4381.78%482.14%3413.33%24-22.58%
Sep 30, 202496-20.00%59,409,677-12.02%471.39%31-41.51%31-6.06%
Jun 30, 2024120-67,526,761-9.69%581.36%53-7.02%336.45%

Top Mutual Funds Shareholders


HolderShares% HoldingChange
T. Rowe Price Small-Cap Value446.29K5.17%-522.00
T. Rowe Price U.S. SC Value Eq Tr-D263.68K3.05%213.59K
Vanguard US Total Market Shares ETF3.42M2.71%-1.00
Vanguard Total Stock Mkt Idx Inv223.22K2.58%-4.88K
Vanguard Explorer Inv133.88K1.55%-
C WorldWide Healthcare Select 1A100.00K1.16%-
Vanguard Institutional Extnd Mkt Idx Tr80.72K0.93%-36.78K
AlphaCentric LifeSci Healthcare I1.13M0.90%-
AlphaCentric Life Sciences & Hlthcare I1.13M0.89%-
Kennedy Micro Cap1.03M0.81%-22.77K

Recent Insider Transactions


DateNameRoleActivityValue
Jul 29, 2025Poulton Stuart EVP, Chief Development OfficerSell$834.67
Jul 22, 2025Abate Kristin Chief Accounting OfficerSell$952.00
May 06, 2025Paulson Richard A. President and CEOSell$1.68K
Apr 23, 2025Rangwala Reshma EVP & Chief Medical OfficerSell$2.59K
Apr 04, 2025Paulson Richard A. President and CEOSell$916.30

Insider Transactions Trends


DateBuySell
2025 Q3-2
2025 Q2-3
2025 Q1-4
2024 Q4-3
2024 Q3-7

KPTI Ownership FAQ


Who Owns Karyopharm Therapeutics?

Karyopharm Therapeutics shareholders are primarily institutional investors at 50.86%, followed by 6.29% insiders and 42.85% retail investors. The average institutional ownership in Karyopharm Therapeutics's industry, Biotech Stocks , is 307.00%, which Karyopharm Therapeutics falls below.

Who owns the most shares of Karyopharm Therapeutics?

Karyopharm Therapeutics’s largest shareholders are T. rowe price investment management (728.77K shares, 8.45%), Adage capital partners gp (421.32K shares, 4.89%), and Blackrock (4.17M shares, 3.61%). Together, they hold 16.95% of Karyopharm Therapeutics’s total shares outstanding.

Does Blackrock own Karyopharm Therapeutics?

Yes, BlackRock owns 3.61% of Karyopharm Therapeutics, totaling 4.17M shares as of Jun 2024. This represents 0.00% of BlackRock's total assets, with a market value of 3.62M$. In the last quarter, BlackRock decreased its holdings by -5.278M shares, a -55.86% change.

Who is Karyopharm Therapeutics’s biggest shareholder by percentage of total assets invested?

Birchview capital, lp is Karyopharm Therapeutics’s biggest shareholder by percentage of total assets invested, with 0.23% of its assets in 419.83K Karyopharm Therapeutics shares, valued at 283.93K$.

Who is the top mutual fund holder of Karyopharm Therapeutics shares?

T. Rowe Price Small-Cap Value is the top mutual fund holder of Karyopharm Therapeutics shares, with 5.17% of its total shares outstanding invested in 446.28K Karyopharm Therapeutics shares.

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