Karyopharm Therapeutics Ownership | Who Owns Karyopharm Therapeutics?
Karyopharm Therapeutics Ownership Summary
Karyopharm Therapeutics is owned by 8.68% institutional investors, 5.81% insiders, and 85.52% retail investors. T. rowe price investment management is the largest institutional shareholder, holding 8.13% of KPTI shares. T. Rowe Price Small-Cap Value is the top mutual fund, with 4.68% of its assets in Karyopharm Therapeutics shares.
KPTI Ownership Benchmark
| Type | Name | % Inst | % Insiders | % Retail |
|---|---|---|---|---|
| Stock | Karyopharm Therapeutics | 8.68% | 5.81% | 85.52% |
| Sector | Healthcare Stocks | 231.98% | 10.74% | -142.72% |
| Industry | Biotech Stocks | 381.47% | 10.55% | -292.02% |
Institutional Shareholders
Top Institutional Shareholders by Total Shares
| Holder | Shares | % Holding | Value |
|---|---|---|---|
| T. rowe price investment management | 700.99K | 8.13% | $4.58M |
| Vanguard group | 559.62K | 6.46% | $4.12M |
| Soleus capital management | 440.00K | 5.08% | $3.24M |
| Adage capital partners gp | 421.32K | 4.89% | $2.76M |
| Blackrock | 4.17M | 3.61% | $3.62M |
| Blackrock funding, inc. /de | 247.56K | 2.86% | $1.82M |
| Geode capital management | 187.73K | 2.17% | $1.38M |
| Catalio capital management, lp | 142.98K | 1.66% | $935.12K |
| Avidity partners management lp | 134.57K | 1.56% | $880.06K |
| Marshall wace, llp | 128.45K | 1.49% | $840.07K |
Top Institutional Shareholders by % of Total Assets
| Holder | Shares | % Assets | Value |
|---|---|---|---|
| Birchview capital, lp | 419.83K | 0.23% | $283.93K |
| Avidity partners management lp | 134.57K | 0.20% | $880.06K |
| Catalio capital management, lp | 142.98K | 0.17% | $935.12K |
| Soleus capital management | 440.00K | 0.12% | $3.24M |
| Silverback asset management | 40.00K | 0.03% | $261.60K |
| Ikarian capital | 27.26K | 0.02% | $178.26K |
| Adar1 capital management | 25.00K | 0.02% | $163.50K |
| C worldwide group | 100.00K | 0.01% | $736.00K |
| Xtx topco | 14.40K | 0.00% | $94.19K |
| Bridgeway capital management | 34.87K | 0.00% | $228.07K |
Top Buyers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Soleus capital management | 440.00K | 0.12% | 440.00K |
| Susquehanna group, llp | 664.14K | 0.00% | 361.60K |
| Vanguard group | 559.62K | 0.00% | 151.40K |
| Alyeska investment group | 144.51K | 0.00% | 144.51K |
| Bank of america corp /de/ | 298.69K | - | 140.77K |
Top Sellers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Blackrock | 4.17M | 0.00% | -5.28M |
| Exome asset management | - | - | -2.00M |
| Opaleye management | - | - | -1.43M |
| Deutsche bank ag\ | - | - | -1.27M |
| Kennedy capital management | - | - | -1.20M |
New Positions
| Holder | Shares | % Assets | Change | Value |
|---|---|---|---|---|
| Soleus capital management | 440.00K | 0.12% | 440.00K | $3.24M |
| Connor, clark & lunn investment management | 57.21K | 0.00% | 57.21K | $421.08K |
| Jane street group | 35.53K | - | 35.53K | $261.52K |
| Adar1 capital management | 25.00K | 0.02% | 25.00K | $163.50K |
| Acadian asset management | 3.73K | - | 3.73K | $27.00K |
Sold Out
| Holder | Change |
|---|---|
| Pittenger & anderson | -3.00 |
| Zurcher kantonalbank (zurich cantonalbank) | -6.00 |
| Farther finance advisors | -13.00 |
| Nelson, van denburg & campbell wealth management group | -22.00 |
| Bruce g. allen investments | -22.00 |
Institutional Ownership Trends
| Date | Holdings | Change % | Shares | Change % | Ownership | Change % | Increased Position | Change % | Decreased Position | Change % |
|---|---|---|---|---|---|---|---|---|---|---|
| Dec 31, 2025 | 12 | -79.31% | 752,172 | -74.49% | 8 | 0.74% | 5 | -72.22% | - | -100.00% |
| Sep 30, 2025 | 18 | -62.50% | 552,924 | -86.33% | 6 | 0.29% | 5 | -79.17% | 3 | -50.00% |
| Jun 30, 2025 | 52 | 4.00% | 4,384,528 | -15.32% | 50 | 281.78% | 27 | 575.00% | 7 | -83.33% |
| Mar 31, 2025 | 51 | -45.74% | 5,312,129 | -91.28% | 4 | 0.17% | 4 | -88.89% | 43 | 86.96% |
| Dec 31, 2024 | 92 | -4.17% | 60,468,438 | 1.78% | 48 | 2.14% | 34 | 13.33% | 24 | -22.58% |
Top Mutual Funds Shareholders
| Holder | Shares | % Holding | Change |
|---|---|---|---|
| T. Rowe Price Small-Cap Value | 858.96K | 4.68% | -36.88K |
| T. Rowe Price U.S. SC Value Eq Tr-D | 585.32K | 3.19% | 319.93K |
| Vanguard Total Stock Mkt Idx Inv | 509.13K | 2.78% | 263.40K |
| Vanguard US Total Market Shares ETF | 3.42M | 2.71% | -1.00 |
| Vanguard Explorer Inv | 133.88K | 1.55% | - |
| Vanguard Institutional Extnd Mkt Idx Tr | 193.82K | 1.06% | - |
| AlphaCentric LifeSci Healthcare I | 1.13M | 0.90% | - |
| AlphaCentric Life Sciences & Hlthcare I | 1.13M | 0.89% | - |
| Kennedy Micro Cap | 1.03M | 0.81% | -22.77K |
| T. Rowe Price U.S. SC Value Eq Tr-Z | 50.09K | 0.60% | 50.09K |
Recent Insider Transactions
| Date | Name | Role | Activity | Value |
|---|---|---|---|---|
| Mar 02, 2026 | Mano Michael | EVP, CLO&Secretary | Sell | $33.18K |
| Mar 02, 2026 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | $43.32K |
| Mar 02, 2026 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | $47.67K |
| Mar 02, 2026 | Paulson Richard A. | President and CEO | Sell | $116.31K |
| Mar 02, 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | $48.00K |
Insider Transactions Trends
| Date | Buy | Sell |
|---|---|---|
| 2026 Q1 | - | 9 |
| 2025 Q4 | - | 1 |
| 2025 Q3 | - | 9 |
| 2025 Q2 | - | 3 |
| 2025 Q1 | - | 4 |
KPTI Ownership FAQ
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