Lexicon Pharmaceuticals Ownership | Who Owns Lexicon Pharmaceuticals?

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Lexicon Pharmaceuticals Ownership Summary

Lexicon Pharmaceuticals is owned by 88.72% institutional investors, 0.98% insiders, and 10.30% retail investors. Artal group is the largest institutional shareholder, holding 43.76% of LXRX shares. Fidelity Growth Compy Commingled Pl O is the top mutual fund, with 5.64% of its assets in Lexicon Pharmaceuticals shares.

LXRX Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Lexicon Pharmaceuticals	88.72%	0.98%	10.30%
Sector	Healthcare Stocks	35.56%	12.08%	52.36%
Industry	Biotech Stocks	35.43%	12.01%	52.56%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Artal group	175.16M	43.76%	$420.37M
Fmr	51.78M	12.94%	$124.28M
Siren	44.30M	11.07%	$106.33M
Sessa capital im	17.91M	4.93%	$27.94M
Blackrock funding, inc. /de	17.35M	4.33%	$41.64M
Blackrock	9.89M	4.03%	$16.62M
Vanguard group	9.61M	2.64%	$11.05M
Vanguard capital management	9.90M	2.47%	$23.76M
Point72 asset management	7.81M	2.15%	$12.19M
Geode capital management	6.24M	1.56%	$14.99M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Artal group	175.16M	45.15%	$420.37M
Siren	44.30M	2.15%	$106.33M
Sessa capital im	17.91M	0.51%	$27.94M
Quantessence capital	18.58K	0.14%	$28.99K
Virtus investment advisers	170.41K	0.10%	$409.00K
R squared	54.98K	0.07%	$131.96K
Gsa capital partners llp	397.22K	0.06%	$953.00K
Headlands	167.20K	0.04%	$401.27K
Straight path wealth management	62.67K	0.04%	$150.40K
Tang capital management	399.70K	0.03%	$623.53K

Top Buyers

Holder	Shares	% Assets	Change
Artal group	175.16M	45.15%	20.42M
Sessa capital im	17.91M	0.51%	14.91M
Blackrock funding, inc. /de	17.35M	0.00%	14.03M
Point72 asset management	7.81M	0.02%	7.53M
Fmr	51.78M	0.01%	6.73M

Top Sellers

Holder	Shares	% Assets	Change
Orbimed advisors	-	-	-11.02M
Nea management company	-	-	-2.38M
Marshall wace, llp	-	-	-2.38M
Ameriprise financial	-	-	-2.33M
Opaleye management	-	-	-1.88M

New Positions

Holder	Shares	% Assets	Change	Value
Nuveen	586.66K	0.00%	586.66K	$1.41M
Tang capital management	399.70K	0.03%	399.70K	$623.53K
Janney montgomery scott	295.55K	0.00%	295.55K	$709.00K
Rhumbline advisers	256.88K	0.00%	256.88K	$616.52K
Deutsche bank ag\	247.53K	0.00%	247.53K	$594.07K

Sold Out

Holder	Change
Ifp advisors	-1.00
True wealth design	-2.00
Newedge advisors	-5.00
Federated hermes	-6.00
Capital performance advisors llp	-18.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Mar 31, 2026	137	7.87%	322,086,781	23.68%	88	1.73%	68	36.00%	27	-32.50%
Dec 31, 2025	31	-76.15%	15,205,811	-94.10%	4	0.08%	7	-85.11%	8	-80.00%
Sep 30, 2025	48	-60.66%	14,323,194	-94.37%	3	0.08%	11	-81.03%	15	-57.14%
Jun 30, 2025	126	-3.82%	256,258,970	-3.59%	70	1.31%	59	-11.94%	38	18.75%
Mar 31, 2025	130	-1.52%	265,798,118	-10.70%	73	1.08%	66	-5.71%	33	32.00%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Fidelity Growth Compy Commingled Pl O	20.40M	5.64%	2.23M
Fidelity Growth Compy Commingled Pl S	24.67M	5.55%	838.50K
Fidelity Growth Company Fund	17.25M	3.88%	705.64K
Vanguard Morn Total Stk Mkt Idx Investor	7.08M	1.59%	236.20K
Vanguard Total Stock Mkt Idx Inv	7.08M	1.59%	236.20K
iShares Russell 2000 ETF	6.19M	1.39%	-109.82K
Fidelity Growth Company K6	5.08M	1.14%	195.76K
Vanguard US Total Market Shares ETF	3.89M	1.08%	-
Fidelity Series Growth Company	4.13M	0.93%	149.60K
Vanguard Institutional Extnd Mkt Idx Tr	2.59M	0.58%	128.78K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Feb 25, 2026	DEBBANE RAYMOND	-	Buy	$2.98K
Feb 23, 2026	DEBBANE RAYMOND	-	Buy	$147.00K
Feb 20, 2026	DEBBANE RAYMOND	-	Buy	$147.79K
Feb 19, 2026	DEBBANE RAYMOND	-	Buy	$71.97K
Feb 18, 2026	DEBBANE RAYMOND	-	Buy	$176.47K

Insider Transactions Trends

Date	Buy	Sell
2026 Q2	-	-
2026 Q1	8	-
2025 Q2	-	-
2025 Q1	-	-
2024 Q4	-	-

LXRX Ownership FAQ

Who Owns Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals shareholders are primarily institutional investors at 88.72%, followed by 0.98% insiders and 10.30% retail investors. The average institutional ownership in Lexicon Pharmaceuticals's industry, Biotech Stocks , is 35.43%, which Lexicon Pharmaceuticals exceeds.

Who owns the most shares of Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals’s largest shareholders are Artal group (175.16M shares, 43.76%), Fmr (51.78M shares, 12.94%), and Siren (44.3M shares, 11.07%). Together, they hold 67.77% of Lexicon Pharmaceuticals’s total shares outstanding.

Does Blackrock own Lexicon Pharmaceuticals?

Yes, BlackRock owns 4.03% of Lexicon Pharmaceuticals, totaling 9.89M shares as of Jun 2024. This represents 0.00% of BlackRock's total assets, with a market value of 16.62M$. In the last quarter, BlackRock increased its holdings by 2.2M shares, a 28.56% change.

Who is Lexicon Pharmaceuticals’s biggest shareholder by percentage of total assets invested?

Artal group is Lexicon Pharmaceuticals’s biggest shareholder by percentage of total assets invested, with 45.15% of its assets in 175.16M Lexicon Pharmaceuticals shares, valued at 420.37M$.

Who is the top mutual fund holder of Lexicon Pharmaceuticals shares?

Fidelity Growth Compy Commingled Pl O is the top mutual fund holder of Lexicon Pharmaceuticals shares, with 5.64% of its total shares outstanding invested in 20.4M Lexicon Pharmaceuticals shares.

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