Lyra Therapeutics Ownership | Who Owns Lyra Therapeutics?

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Lyra Therapeutics Ownership Summary

Lyra Therapeutics is owned by 33.26% institutional investors, 0.67% insiders, and 66.07% retail investors. Perceptive advisors is the largest institutional shareholder, holding 17.01% of LYRA shares. iShares Russell 2000 ETF is the top mutual fund, with 3.38% of its assets in Lyra Therapeutics shares.

LYRA Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Lyra Therapeutics	33.26%	0.67%	66.07%
Sector	Healthcare Stocks	42.54%	10.83%	46.63%
Industry	Biotech Stocks	45.22%	10.75%	44.04%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Perceptive advisors	229.38K	17.01%	$1.50M
Sabby management	127.62K	9.46%	$832.87K
Blackrock	2.83M	4.42%	$783.05K
Vanguard group	28.75K	2.13%	$189.49K
Ikarian capital	21.16K	1.57%	$139.45K
Goldman sachs group	555.51K	0.85%	$114.66K
Geode capital management	10.99K	0.81%	$72.41K
Caption management	246.60K	0.39%	$68.23K
Ubs group	4.00K	0.30%	$26.11K
Susquehanna group, llp	103.43K	0.16%	$21.35K

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Sabby management	127.62K	0.96%	$832.87K
Perceptive advisors	229.38K	0.04%	$1.50M
Ikarian capital	21.16K	0.01%	$139.45K
Signature resources capital management	400.00	0.00%	$2.61K
Caption management	246.60K	0.00%	$68.23K
Fortitude family office	96.00	0.00%	$627.00
Eversource wealth advisors	345.00	0.00%	$2.25K
Tower research capital llc (trc)	534.00	0.00%	$3.48K
National bank of canada /fi/	-	-	-
Valley national advisers	-	-	-

Top Buyers

Holder	Shares	% Assets	Change
Blackrock	2.83M	-	2.68M
Caption management	246.60K	0.00%	246.60K
Susquehanna group, llp	103.43K	-	90.52K
Goldman sachs group	555.51K	-	8.17K
Ubs group	4.00K	-	4.00K

Top Sellers

Holder	Shares	% Assets	Change
Nantahala capital management	-	-	-2.82M
Point72 asset management	-	-	-2.74M
Vr adviser	-	-	-2.58M
Pura vida investments	-	-	-1.41M
Samsara biocapital	-	-	-1.39M

New Positions

Holder	Shares	% Assets	Change	Value
Caption management	246.60K	0.00%	246.60K	$68.23K
Fortitude family office	96.00	0.00%	96.00	$627.00
Advisor group	22.00	-	22.00	$143.00
Bryn mawr trust	20.00	-	20.00	$131.00

Sold Out

Holder	Change
Raymond james financial	-8.00
Nisa investment advisors	-10.00
Principal securities	-19.00
Farther finance advisors	-38.00
Wells fargo & company/mn	-39.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Sep 30, 2025	24	-14.29%	448,586	-8.79%	33	2.50%	9	-10.00%	10	-44.44%
Jun 30, 2025	29	-49.12%	493,995	-98.07%	36	2.54%	10	-50.00%	19	-
Mar 31, 2025	5	-90.74%	15,783,037	-41.30%	24	1.42%	1	-96.43%	1	-91.67%
Dec 31, 2024	54	-12.90%	26,885,924	-17.35%	41	1.66%	28	-12.50%	12	-14.29%
Sep 30, 2024	61	15.09%	32,528,511	-0.62%	49	1.90%	31	10.71%	14	7.69%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
iShares Russell 2000 ETF	44.78K	3.38%	-
Vanguard US Total Market Shares ETF	992.54K	1.51%	2.00
Vanguard Total Stock Mkt Idx Inv	19.43K	1.20%	-424.00
iShares Russell 2000 Growth ETF	408.38K	0.62%	-
Fidelity Small Cap Index	6.33K	0.40%	-
Vanguard Institutional Extnd Mkt Idx Tr	6.26K	0.39%	-2.85K
Fidelity Extended Market Index	5.41K	0.33%	-38.00
Vanguard Russell 2000 ETF	4.83K	0.30%	24.00
Russell 3000 Screened Index Composite	186.70K	0.29%	186.70K
Spartan Total Market Index Pool E	140.13K	0.21%	-

Recent Insider Transactions

Date	Name	Role	Activity	Value
Nov 13, 2025	PERCEPTIVE ADVISORS LLC	-	Sell	$111.53K
Nov 11, 2025	PERCEPTIVE ADVISORS LLC	-	Sell	$2.32K
Nov 11, 2025	PERCEPTIVE ADVISORS LLC	-	Sell	$20.64K
Nov 12, 2025	PERCEPTIVE ADVISORS LLC	-	Sell	$31.91K
Nov 12, 2025	PERCEPTIVE ADVISORS LLC	-	Sell	$3.58K

Insider Transactions Trends

Date	Buy	Sell
2025 Q4	-	12
2025 Q3	-	2
2025 Q2	-	-
2025 Q1	-	-
2024 Q4	-	-

LYRA Ownership FAQ

Who Owns Lyra Therapeutics?

Lyra Therapeutics shareholders are primarily institutional investors at 33.26%, followed by 0.67% insiders and 66.07% retail investors. The average institutional ownership in Lyra Therapeutics's industry, Biotech Stocks , is 45.22%, which Lyra Therapeutics falls below.

Who owns the most shares of Lyra Therapeutics?

Lyra Therapeutics’s largest shareholders are Perceptive advisors (229.38K shares, 17.01%), Sabby management (127.62K shares, 9.46%), and Blackrock (2.83M shares, 4.42%). Together, they hold 30.89% of Lyra Therapeutics’s total shares outstanding.

Does Blackrock own Lyra Therapeutics?

Yes, BlackRock owns 4.42% of Lyra Therapeutics, totaling 2.83M shares as of Jun 2024. This represents 0% of BlackRock's total assets, with a market value of 783.06K$. In the last quarter, BlackRock increased its holdings by 2.68M shares, a 1762.82% change.

Who is Lyra Therapeutics’s biggest shareholder by percentage of total assets invested?

Sabby management is Lyra Therapeutics’s biggest shareholder by percentage of total assets invested, with 0.96% of its assets in 127.62K Lyra Therapeutics shares, valued at 832.87K$.

Who is the top mutual fund holder of Lyra Therapeutics shares?

iShares Russell 2000 ETF is the top mutual fund holder of Lyra Therapeutics shares, with 3.38% of its total shares outstanding invested in 44.78K Lyra Therapeutics shares.

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