OPKO Health (OPK) Revenue & Revenue Breakdown

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OPKO Health Revenue Highlights

Latest Revenue (Y)

$606.89M

Latest Revenue (Q)

$124.20M

Main Segment (Y)

Service

Main Geography (Y)

UNITED STATES

OPKO Health Revenue by Period

OPKO Health Revenue by Year

Date	Revenue	Change
2025-12-31	$606.89M	-14.90%
2024-12-31	$713.14M	-17.41%
2023-12-31	$863.50M	-14.01%
2022-12-31	$1.00B	-43.42%
2021-12-31	$1.77B	23.64%
2020-12-31	$1.44B	59.15%
2019-12-31	$901.93M	-8.92%
2018-12-31	$990.30M	2.51%
2017-12-31	$966.01M	-20.93%
2016-12-31	$1.22B	148.46%
2015-12-31	$491.70M	439.74%
2014-12-31	$91.10M	-5.63%
2013-12-31	$96.53M	105.19%
2012-12-31	$47.04M	68.14%
2011-12-31	$27.98M	-1.81%
2010-12-31	$28.49M	116.73%
2009-12-31	$13.15M	39.27%
2008-12-31	$9.44M	1014.52%
2007-12-31	$847.00K	100.00%
2006-12-31	-	100.00%
2005-12-31	-	100.00%
2004-12-31	-	-100.00%
2003-12-31	$13.00K	-97.69%
2002-12-31	$562.00K	-57.84%
2001-12-31	$1.33M	54.10%
2000-12-31	$865.00K	-37.09%
1999-12-31	$1.38M	14.58%
1998-12-31	$1.20M	1100.00%
1997-12-31	$100.00K	-
1996-12-31	$100.00K	-
1995-12-31	$100.00K	-

OPKO Health generated $606.89M in revenue during NA 2025, up -14.90% compared to the previous quarter, and up 42.28% compared to the same period a year ago.

OPKO Health Revenue by Quarter

Date	Revenue	Change
2026-03-31	$124.20M	-16.37%
2025-12-31	$148.50M	-2.09%
2025-09-30	$151.67M	-3.28%
2025-06-30	$156.81M	4.57%
2025-03-31	$149.95M	-18.34%
2024-12-31	$183.64M	5.76%
2024-09-30	$173.63M	-4.70%
2024-06-30	$182.19M	4.89%
2024-03-31	$173.69M	-4.52%
2023-12-31	$181.90M	1.85%
2023-09-30	$178.59M	-32.71%
2023-06-30	$265.42M	11.72%
2023-03-31	$237.58M	28.18%
2022-12-31	$185.34M	3.11%
2022-09-30	$179.74M	-42.00%
2022-06-30	$309.89M	-5.87%
2022-03-31	$329.22M	-17.97%
2021-12-31	$401.33M	4.02%
2021-09-30	$385.81M	-12.79%
2021-06-30	$442.41M	-18.85%
2021-03-31	$545.16M	10.22%
2020-12-31	$494.60M	15.54%
2020-09-30	$428.06M	42.12%
2020-06-30	$301.21M	42.44%
2020-03-31	$211.47M	-5.74%
2019-12-31	$224.34M	-1.94%
2019-09-30	$228.77M	1.06%
2019-06-30	$226.37M	1.74%
2019-03-31	$222.50M	0.27%
2018-12-31	$221.90M	-11.17%
2018-09-30	$249.81M	-5.26%
2018-06-30	$263.69M	3.45%
2018-03-31	$254.90M	31.60%
2017-12-31	$193.70M	-26.49%
2017-09-30	$263.50M	-16.14%
2017-06-30	$314.21M	6.12%
2017-03-31	$296.10M	7.48%
2016-12-31	$275.50M	-7.55%
2016-09-30	$298.00M	-16.55%
2016-06-30	$357.10M	22.70%
2016-03-31	$291.04M	5.38%
2015-12-31	$276.19M	93.09%
2015-09-30	$143.03M	237.11%
2015-06-30	$42.43M	41.04%
2015-03-31	$30.08M	17.82%
2014-12-31	$25.53M	29.13%
2014-09-30	$19.77M	-16.02%
2014-06-30	$23.55M	5.71%
2014-03-31	$22.27M	7.65%
2013-12-31	$20.69M	0.25%
2013-09-30	$20.64M	-13.35%
2013-06-30	$23.82M	-24.08%
2013-03-31	$31.38M	92.95%
2012-12-31	$16.26M	37.86%
2012-09-30	$11.79M	15.51%
2012-06-30	$10.21M	16.34%
2012-03-31	$8.78M	51.48%
2011-12-31	$5.79M	-14.88%
2011-09-30	$6.81M	-32.88%
2011-06-30	$10.14M	17.28%
2011-03-31	$8.65M	-37.80%
2010-12-31	$13.90M	82.97%
2010-09-30	$7.60M	1.93%
2010-06-30	$7.46M	-5.89%
2010-03-31	$7.92M	13.20%
2009-12-31	$7.00M	366.22%
2009-09-30	$1.50M	-36.05%
2009-06-30	$2.35M	2.00%
2009-03-31	$2.30M	36.40%
2008-12-31	$1.69M	-58.35%
2008-09-30	$4.05M	360.75%
2008-06-30	$879.00K	-68.87%
2008-03-31	$2.82M	100.00%
2007-12-31	-	-

OPKO Health generated $124.20M in revenue during Q1 2026, up -16.37% compared to the previous quarter, and up 67.63% compared to the same period a year ago.

OPKO Health Revenue Breakdown

OPKO Health Revenue Breakdown by Product

Annual Revenue by Product

Product/Service	Dec 25	Dec 24	Dec 23	Dec 22	Dec 21
Product	$156.92M	$155.11M	$167.56M	$142.84M	$141.77M
Transfer of Intellectual Property and Other	$79.68M	$77.36M	-	-	-
Service	$370.27M	$480.67M	$515.27M	$755.63M	$1.61B
Rayaldee	-	-	-	$59.56M	$64.30M
Client Payers	-	-	-	$316.31M	$843.40M
Health Insurers	-	-	-	$326.14M	$520.24M
Government Payers	-	-	-	$97.19M	$222.24M
Patients	-	-	-	$15.99M	$21.21M
Transfer Of Intellectual Property And Other	-	-	-	$105.72M	$25.84M

OPKO Health's latest annual revenue breakdown by segment (product or service), as of Dec 25: Service (61.01%), Product (25.86%), and Transfer of Intellectual Property and Other (13.13%).

Quarterly Revenue by Product

Product/Service	Mar 26	Dec 25	Sep 25	Jun 25	Mar 25	Dec 24	Sep 24	Mar 24	Dec 23	Sep 23	Jun 23	Mar 23	Dec 22	Sep 22	Jun 22	Mar 22	Dec 21	Sep 21	Jun 21	Mar 21
Transfer of Intellectual Property and Other	$13.97M	$33.70M	$18.75M	$14.96M	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Product	$38.04M	$43.66M	$37.68M	$40.74M	$34.84M	$77.92M	$39.14M	$38.05M	$83.39M	$40.67M	$43.50M	$37.91M	$32.39M	$35.89M	$36.66M	$35.28M	$36.88M	$35.66M	$33.95M	-
Service	$72.19M	$71.09M	$95.24M	$101.10M	$102.84M	$232.51M	$121.27M	$126.89M	$251.23M	$131.68M	$132.37M	$139.37M	$142.86M	$186.80M	$286.60M	$362.79M	$340.16M	$397.20M	$506.95M	-
Rayaldee	-	-	-	-	-	-	-	-	-	-	$17.57M	$16.20M	$14.50M	$15.38M	$13.48M	$17.20M	$15.33M	$16.12M	$15.64M	-
Client Payers	-	-	-	-	-	-	-	-	-	-	-	$27.17M	$29.89M	$61.70M	$80.93M	$159.04M	$185.93M	$168.64M	$225.94M	$262.91M
Government Payers	-	-	-	-	-	-	-	-	-	-	-	$20.42M	$22.25M	$20.15M	$25.66M	$27.59M	$42.77M	$48.20M	$57.61M	$73.66M
Health Insurers	-	-	-	-	-	-	-	-	-	-	-	$80.60M	$83.23M	$58.08M	$76.44M	$95.78M	$128.47M	$117.89M	$109.08M	$164.83M
Patients	-	-	-	-	-	-	-	-	-	-	-	$4.18M	$4.00M	$2.93M	$3.77M	$4.19M	$5.63M	$5.43M	$4.57M	$5.56M
Transfer Of Intellectual Property And Other	-	-	-	-	-	-	-	-	-	-	-	-	$8.06M	$4.50M	$87.20M	$5.96M	$3.26M	$8.77M	$9.55M	-

OPKO Health's latest quarterly revenue breakdown by segment (product or service), as of Mar 26: Service (58.12%), Product (30.63%), and Transfer of Intellectual Property and Other (11.25%).

OPKO Health Revenue Breakdown by Country

Annual Revenue by Country

Country	Dec 25	Dec 24	Dec 23	Dec 22	Dec 21
SPAIN	$26.73M	$24.63M	$23.52M	$22.48M	$22.68M
UNITED STATES	$436.06M	$546.30M	$597.82M	$783.21M	$1.64B
MEXICO	$25.52M	$23.87M	$20.22M	$14.55M	$11.01M
ISRAEL	$522.00K	$1.77M	$9.74M	$3.85M	$3.56M
Other Countries	$4.27M	$3.12M	$2.25M	$863.00K	$507.00K
IRELAND	$51.40M	$48.40M	$141.47M	$117.21M	$32.81M
CHILE	$62.38M	$65.05M	$68.49M	$62.04M	$63.80M

OPKO Health's latest annual revenue breakdown by geography, as of Dec 25: UNITED STATES (71.85%), CHILE (10.28%), IRELAND (8.47%), SPAIN (4.40%), MEXICO (4.21%), Other Countries (0.70%), and ISRAEL (0.09%).

Quarterly Revenue by Country

Country	Mar 26	Dec 25	Sep 25	Jun 25	Mar 25	Dec 24	Sep 24	Mar 24	Dec 23	Sep 23	Jun 23	Mar 23	Dec 22	Sep 22	Jun 22	Mar 22	Dec 21	Sep 21	Jun 21	Mar 21
IRELAND	$9.68M	$22.10M	$12.08M	$11.74M	$5.48M	$27.66M	$11.51M	$9.22M	$20.22M	$8.65M	$96.75M	$15.85M	$12.90M	$6.68M	$89.18M	$8.46M	$8.15M	$5.45M	$12.09M	$7.13M
CHILE	$14.87M	$17.48M	$14.36M	$16.00M	$14.53M	$33.58M	$16.58M	$14.89M	$16.06M	$16.93M	$19.95M	$15.54M	$15.55M	$14.35M	$15.80M	$16.34M	$14.50M	$16.49M	$18.66M	$14.15M
SPAIN	$8.05M	$7.22M	$6.34M	$6.72M	$6.44M	$12.68M	$6.30M	$5.66M	$7.09M	$4.35M	$5.97M	$6.11M	$5.11M	$4.56M	$5.70M	$7.11M	$5.61M	$5.72M	$5.44M	$5.92M
UNITED STATES	$83.50M	$94.05M	$110.92M	$114.88M	$116.21M	$277.59M	$132.66M	$136.04M	$134.84M	$139.04M	$134.86M	$189.09M	$148.45M	$149.84M	$193.10M	$291.81M	$370.61M	$354.59M	$402.29M	$512.87M
Other Countries	$1.15M	$1.17M	$1.09M	$1.02M	$992.00K	$1.74M	$756.00K	$630.00K	$581.00K	$565.00K	$525.00K	$575.00K	$293.00K	$174.00K	$202.00K	$193.00K	$65.00K	$106.00K	$172.00K	$164.00K
MEXICO	$6.94M	$6.26M	$6.74M	$6.30M	$6.23M	$11.15M	$5.63M	$7.08M	$2.77M	$5.90M	$5.72M	$5.83M	$2.85M	$3.89M	$4.05M	$3.75M	$2.39M	$3.16M	$3.04M	$2.42M
ISRAEL	-	$170.00K	$140.00K	$139.00K	$73.00K	$1.42M	$196.00K	$160.00K	$350.00K	$3.15M	$1.64M	$4.59M	$182.00K	$251.00K	$1.85M	$1.56M	$20.00K	$307.00K	$724.00K	$2.51M

OPKO Health's latest quarterly revenue breakdown by geography, as of Mar 26: UNITED STATES (67.24%), CHILE (11.97%), IRELAND (7.79%), SPAIN (6.48%), MEXICO (5.59%), and Other Countries (0.93%).

OPKO Health Peer Comparison by Revenue

Ticker	Company	Last Year Revenue	Last Quarter Revenue
TNDM	Tandem Diabetes Care	$1.01B	$247.22M
CTEV	Claritev	$965.41M	$244.68M
PCRX	Pacira BioSciences	$726.41M	$177.38M
OPK	OPKO Health	$606.89M	$124.20M
LFMD	LifeMD	$194.06M	$50.16M
NKTR	Nektar Therapeutics	$55.23M	$10.86M
DNTH	Dianthus Therapeutics	$2.04M	-
OCS	Oculis	$883.00K	-
PSNL	Personalis	-	-
SANA	Sana Bio	-	-
XNCR	Xencor	-	$43.61M

OPK Revenue FAQ

What is OPKO Health’s yearly revenue?

OPKO Health's yearly revenue for 2025 was $606.89M, representing a decrease of -14.90% compared to 2024. The company's yearly revenue for 2024 was $713.14M, representing a decrease of -17.41% compared to 2023. OPK's yearly revenue for 2023 was $863.5M, representing a decrease of -14.01% compared to 2022.

What is OPKO Health’s quarterly revenue?

OPKO Health's quarterly revenue for Q1 2026 was $124.2M, a -16.37% decrease from the previous quarter (Q4 2025), and a -17.18% decrease year-over-year (Q1 2025). The company's quarterly revenue for Q4 2025 was $148.5M, a -2.09% decrease from the previous quarter (Q3 2025), and a -19.13% decrease year-over-year (Q4 2024). OPK's quarterly revenue for Q3 2025 was $151.67M, a -3.28% decrease from the previous quarter (Q2 2025), and a -12.65% decrease year-over-year (Q3 2024).

What is OPKO Health’s revenue growth rate?

OPKO Health's revenue growth rate for the last 3 years (2023-2025) was -29.72%, and for the last 5 years (2021-2025) was -65.80%.

What are OPKO Health’s revenue streams?

OPKO Health's revenue streams in c 25 are Product, Transfer of Intellectual Property and Other, and Service. Product generated $156.92M in revenue, accounting 25.86% of the company's total revenue, up 1.17% year-over-year. Transfer of Intellectual Property and Other generated $79.68M in revenue, accounting 13.13% of the company's total revenue, up 2.99% year-over-year. Service generated $370.28M in revenue, accounting 61.01% of the company's total revenue, down -22.97% year-over-year.

What is OPKO Health’s main source of revenue?

For the fiscal year ending Dec 25, the largest source of revenue of OPKO Health was Service. This segment made a revenue of $370.28M, representing 61.01% of the company's total revenue.