Prelude Therapeutics Ownership | Who Owns Prelude Therapeutics?

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Prelude Therapeutics Ownership Summary

Prelude Therapeutics is owned by 2.11% institutional investors, 13.80% insiders, and 84.10% retail investors. Orbimed advisors is the largest institutional shareholder, holding 14.18% of PRLD shares. Vanguard Total Stock Mkt Idx Inv is the top mutual fund, with 1.49% of its assets in Prelude Therapeutics shares.

PRLD Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Prelude Therapeutics	2.11%	13.80%	84.10%
Sector	Healthcare Stocks	35.49%	11.75%	52.76%
Industry	Biotech Stocks	34.83%	11.71%	53.46%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Orbimed advisors	10.91M	14.18%	$37.31M
Baker bros. advisors lp	10.12M	13.16%	$34.62M
Boxer capital	2.57M	3.39%	$9.79M
Kynam capital management, lp	1.59M	2.07%	$5.45M
Vanguard group	1.41M	1.86%	$4.10M
Blackrock	1.07M	1.41%	$4.07M
Ecor1 capital	947.05K	1.23%	$3.24M
Two sigma investments, lp	923.63K	1.20%	$3.16M
Sphera funds management	558.34K	0.73%	$1.91M
Acadian asset management	511.52K	0.66%	$1.75M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Orbimed advisors	10.91M	0.74%	$37.31M
Boxer capital	2.57M	0.52%	$9.79M
Kynam capital management, lp	1.59M	0.34%	$5.45M
Sphera funds management	558.34K	0.30%	$1.91M
Baker bros. advisors lp	10.12M	0.20%	$34.62M
Ecor1 capital	947.05K	0.14%	$3.24M
Shay capital	100.00K	0.01%	$144.00K
Diametric capital, lp	11.98K	0.01%	$40.97K
Nine masts capital	11.70K	0.01%	$40.01K
Bridgeway capital management	53.50K	0.00%	$182.97K

Top Buyers

Holder	Shares	% Assets	Change
Ecor1 capital	947.05K	0.14%	947.05K
Kynam capital management, lp	1.59M	0.34%	803.68K
Sphera funds management	558.34K	0.30%	435.59K
Vanguard group	1.41M	0.00%	421.13K
Millennium management	382.74K	0.00%	231.74K

Top Sellers

Holder	Shares	% Assets	Change
Deerfield management company, l.p. (series c)	-	-	-3.77M
Exoduspoint capital management, lp	-	-	-921.62K
Avidity partners management lp	-	-	-890.00K
Price t rowe associates inc /md/	-	-	-755.96K
Massachusetts financial services co /ma/	-	-	-494.50K

New Positions

Holder	Shares	% Assets	Change	Value
Ecor1 capital	947.05K	0.14%	947.05K	$3.24M
Vanguard fiduciary trust	157.38K	0.00%	157.38K	$538.24K
Citadel advisors	124.38K	0.00%	124.38K	$425.37K
Dimensional fund advisors lp	35.21K	-	35.21K	$119.69K
Aqr capital management	12.49K	-	12.49K	$15.93K

Sold Out

Holder	Change
Ifp advisors	-1.00
Nelson, van denburg & campbell wealth management group	-1.00
Capital performance advisors llp	-8.00
True wealth design	-13.00
Srs capital advisors	-15.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Mar 31, 2026	13	-73.47%	1,621,555	-94.30%	2	0.15%	8	-66.67%	2	-86.67%
Dec 31, 2025	26	-42.22%	4,054,360	-85.07%	5	0.42%	12	-20.00%	9	-52.63%
Sep 30, 2025	44	-2.22%	27,161,948	1.82%	35	2.90%	15	-11.76%	18	-14.29%
Jun 30, 2025	49	-14.04%	27,188,001	-4.17%	35	2.57%	19	-9.52%	23	-4.17%
Mar 31, 2025	57	-6.56%	30,474,260	-5.26%	40	2.23%	22	-35.29%	24	118.18%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard Total Stock Mkt Idx Inv	936.00K	1.49%	-
Vanguard US Total Market Shares ETF	720.43K	1.31%	-
T. Rowe Price Health Sciences	516.22K	0.82%	-40.53K
MFS New Discovery I	327.70K	0.60%	-
Biotech Growth Ord	346.50K	0.44%	-
Vanguard Institutional Extnd Mkt Idx Tr	263.16K	0.42%	-22.14K
T. Rowe Price Small-Cap Value	168.61K	0.31%	-90.00
Fidelity Small Cap Index	144.77K	0.26%	-
MFS VIT New Discovery Init	104.99K	0.19%	-
State St Russell Sm/Mid Cp® Indx NL Cl C	104.70K	0.19%	-

Recent Insider Transactions

Date	Name	Activity	Value
Apr 21, 2026	Bonita David P	Buy	$7.50M
Apr 21, 2026	Bonita David P	Buy	$5.00M
Apr 21, 2026	ORBIMED ADVISORS LLC	Buy	$5.00M
Apr 21, 2026	ORBIMED ADVISORS LLC	Buy	$7.50M
Apr 21, 2026	BAKER BROS. ADVISORS LP	Buy	$213.77

Insider Transactions Trends

Date	Buy	Sell
2026 Q2	6	-
2026 Q1	-	-
2025 Q4	-	-
2025 Q3	-	-
2025 Q2	-	-

PRLD Ownership FAQ

Who Owns Prelude Therapeutics?

Prelude Therapeutics shareholders are primarily institutional investors at 2.11%, followed by 13.80% insiders and 84.09% retail investors. The average institutional ownership in Prelude Therapeutics's industry, Biotech Stocks , is 34.83%, which Prelude Therapeutics falls below.

Who owns the most shares of Prelude Therapeutics?

Prelude Therapeutics’s largest shareholders are Orbimed advisors (10.91M shares, 14.18%), Baker bros. advisors lp (10.12M shares, 13.16%), and Boxer capital (2.57M shares, 3.39%). Together, they hold 30.72% of Prelude Therapeutics’s total shares outstanding.

Does Blackrock own Prelude Therapeutics?

Yes, BlackRock owns 1.41% of Prelude Therapeutics, totaling 1.07M shares as of Jun 2024. This represents 0.00% of BlackRock's total assets, with a market value of 4.07M$. In the last quarter, BlackRock decreased its holdings by -28.558K shares, a -2.60% change.

Who is Prelude Therapeutics’s biggest shareholder by percentage of total assets invested?

Orbimed advisors is Prelude Therapeutics’s biggest shareholder by percentage of total assets invested, with 0.74% of its assets in 10.91M Prelude Therapeutics shares, valued at 37.31M$.

Who is the top mutual fund holder of Prelude Therapeutics shares?

Vanguard Total Stock Mkt Idx Inv is the top mutual fund holder of Prelude Therapeutics shares, with 1.49% of its total shares outstanding invested in 936K Prelude Therapeutics shares.

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