Spruce Biosciences Ownership | Who Owns Spruce Biosciences?

Spruce Biosciences Ownership Summary

Spruce Biosciences is owned by 82.63% institutional investors, 3.37% insiders, and 13.99% retail investors. Ikarian capital is the largest institutional shareholder, holding 15.83% of SPRB shares. Vanguard Total Stock Mkt Idx Inv is the top mutual fund, with 3.09% of its assets in Spruce Biosciences shares.

SPRB Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Spruce Biosciences	82.63%	3.37%	13.99%
Sector	Healthcare Stocks	244.59%	12.11%	-156.70%
Industry	Biotech Stocks	379.61%	11.70%	-291.31%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Ikarian capital	121.36K	15.83%	$7.93M
Millennium management	111.89K	14.60%	$7.31M
Citadel advisors	70.00K	9.13%	$4.57M
Rivervest venture management	2.94M	7.14%	$1.52M
Alyeska investment group	51.67K	6.74%	$3.38M
Rock springs capital management lp	2.61M	6.32%	$1.10M
Boothbay fund management	42.08K	5.49%	$2.75M
Balyasny asset management	40.00K	5.22%	$2.61M
Carlyle group	38.62K	5.04%	$2.52M
Quinn opportunity partners	26.81K	3.50%	$1.75M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Rivervest venture management	2.94M	22.27%	$1.52M
Ikarian capital	121.36K	0.64%	$7.93M
Lion point capital, lp	1.00K	0.39%	$65.35K
Diadema partners lp	10.00K	0.11%	$653.50K
Quinn opportunity partners	26.81K	0.09%	$1.75M
Stempoint capital lp	6.36K	0.08%	$415.63K
Persistent asset partners	2.53K	0.06%	$165.21K
Rock springs capital management lp	2.61M	0.04%	$1.10M
Boothbay fund management	42.08K	0.04%	$2.75M
Carlyle group	38.62K	0.02%	$2.52M

Top Buyers

Holder	Shares	% Assets	Change
Millennium management	111.89K	0.00%	111.89K
Susquehanna group, llp	58.98K	-	58.98K
Diadema partners lp	10.00K	0.11%	10.00K
Stempoint capital lp	6.36K	0.08%	6.36K
Vanguard fiduciary trust	5.51K	0.00%	5.51K

Top Sellers

Holder	Shares	% Assets	Change
Rosalind advisors	-	-	-1.51M
Aisling capital management lp	-	-	-1.21M
Acadian asset management	-	-	-1.05M
Vanguard group	-	-	-843.84K
Altium capital management lp	-	-	-811.17K

New Positions

Holder	Shares	% Assets	Change	Value
Millennium management	111.89K	0.00%	111.89K	$7.31M
Susquehanna group, llp	58.98K	-	58.98K	$24.77K
Diadema partners lp	10.00K	0.11%	10.00K	$653.50K
Stempoint capital lp	6.36K	0.08%	6.36K	$415.63K
Vanguard fiduciary trust	5.51K	0.00%	5.51K	$360.34K

Sold Out

Holder	Change
Qube research	-2.00
Royal bank of canada	-40.00
Jpmorgan chase	-65.00
Fmr	-103.00
Wells fargo & company/mn	-143.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Jun 30, 2026	64	100.00%	2,008,845	171.55%	82	2.84%	52	225.00%	3	-50.00%
Mar 31, 2026	32	-	739,765	-1.87%	96	0.54%	16	-44.83%	6	500.00%
Dec 31, 2025	32	255.56%	753,855	-74.34%	133	0.05%	29	314.29%	1	-50.00%
Sep 30, 2025	9	200.00%	2,937,895	43.53%	521	2575.15%	7	-	2	-
Jun 30, 2025	3	-89.29%	2,046,828	-73.79%	4	1.51%	-	-100.00%	-	-100.00%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard Total Stock Mkt Idx Inv	84.94K	3.09%	8.70K
Vanguard Morn Total Stk Mkt Idx Investor	84.94K	3.09%	8.70K
Vanguard MStar Total Stk Mkt Idx Invest	84.94K	3.09%	-
Biotech Growth Ord	67.80K	2.46%	-
iShares Russell 2000 ETF	67.25K	2.44%	-1.15K
Vanguard US Total Market Shares ETF	638.56K	1.55%	-
Vanguard Institutional Extnd Mkt Idx Tr	31.89K	1.16%	-
iShares Russell 2000 Value ETF	17.45K	0.63%	-
Russell 2000 Equity Index Fund B	17.40K	0.63%	17.40K
Russell 2000 Index Non-Lendable Fund	17.40K	0.63%	17.40K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Buy	$4.59K
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Sell	$436.39
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Sell	$4.48K
Mar 21, 2024	Novo Holdings A/S	-	Sell	$350.95K
Mar 19, 2024	Novo Holdings A/S	-	Sell	$447.71K

Insider Transactions Trends

Date	Buy	Sell
2026 Q3	-	-
2026 Q2	-	-
2026 Q1	-	-
2025 Q4	1	2
2025 Q3	-	-

SPRB Ownership FAQ

Who Owns Spruce Biosciences?

Spruce Biosciences shareholders are primarily institutional investors at 82.63%, followed by 3.37% insiders and 14.00% retail investors. The average institutional ownership in Spruce Biosciences's industry, Biotech Stocks , is 379.61%, which Spruce Biosciences falls below.

Who owns the most shares of Spruce Biosciences?

Spruce Biosciences’s largest shareholders are Ikarian capital (121.36K shares, 15.83%), Millennium management (111.89K shares, 14.60%), and Citadel advisors (70K shares, 9.13%). Together, they hold 39.56% of Spruce Biosciences’s total shares outstanding.

Does Blackrock own Spruce Biosciences?

BlackRock is not among the top 10 institutional shareholders of Spruce Biosciences.

Who is Spruce Biosciences’s biggest shareholder by percentage of total assets invested?

Rivervest venture management is Spruce Biosciences’s biggest shareholder by percentage of total assets invested, with 22.27% of its assets in 2.94M Spruce Biosciences shares, valued at 1.52M$.

Who is the top mutual fund holder of Spruce Biosciences shares?

Vanguard Total Stock Mkt Idx Inv is the top mutual fund holder of Spruce Biosciences shares, with 3.09% of its total shares outstanding invested in 84.94K Spruce Biosciences shares.

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