Spruce Biosciences Ownership | Who Owns Spruce Biosciences?

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Spruce Biosciences Ownership Summary

Spruce Biosciences is owned by 133.88% institutional investors, 9.12% insiders. Rivervest venture management is the largest institutional shareholder, holding 7.14% of SPRB shares. Vanguard Institutional Extnd Mkt Idx Tr is the top mutual fund, with 2.11% of its assets in Spruce Biosciences shares.

SPRB Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Spruce Biosciences	133.88%	9.12%	-43.00%
Sector	Healthcare Stocks	232.01%	10.74%	-142.75%
Industry	Biotech Stocks	381.47%	10.55%	-292.02%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Rivervest venture management	2.94M	7.14%	$1.52M
Rock springs capital management lp	2.61M	6.32%	$1.10M
Blackrock	124.73K	0.30%	$64.58K
Susquehanna group, llp	58.98K	0.14%	$24.77K
Charles schwab investment management	15.29K	0.04%	$7.92K
Citadel advisors	14.30K	0.03%	$7.40K
Morgan stanley	2.13K	0.01%	$1.10K
Bnp paribas arbitrage, snc	181.00	0.00%	$76.00
Bank of america corp /de/	150.00	0.00%	$78.00
Tower research capital llc (trc)	-	-	-

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Rivervest venture management	2.94M	22.27%	$1.52M
Rock springs capital management lp	2.61M	0.04%	$1.10M
Renaissance	-	-	-
Blackrock	124.73K	-	$64.58K
Two sigma advisers, lp	-	-	-
Tower research capital llc (trc)	-	-	-
Lion point capital, lp	-	-	-
Almitas capital	-	-	-
Two sigma securities	-	-	-
Marshall wace, llp	-	-	-

Top Buyers

Holder	Shares	% Assets	Change
Susquehanna group, llp	58.98K	-	58.98K
Citadel advisors	14.30K	-	4.40K
Bnp paribas arbitrage, snc	181.00	-	181.00
Rivervest venture management	2.94M	22.27%	-
Rock springs capital management lp	2.61M	0.04%	-

Top Sellers

Holder	Shares	% Assets	Change
Carlyle group	-	-	-2.90M
Rosalind advisors	-	-	-1.51M
Aisling capital management lp	-	-	-1.21M
Acadian asset management	-	-	-1.05M
Ikarian capital	-	-	-1.00M

New Positions

Holder	Shares	% Assets	Change	Value
Susquehanna group, llp	58.98K	-	58.98K	$24.77K
Bnp paribas arbitrage, snc	181.00	-	181.00	$76.00

Sold Out

Holder	Change
Qube research	-2.00
Jpmorgan chase	-65.00
Fmr	-103.00
Wells fargo & company/mn	-143.00
Caldwell sutter capital	-1.00K

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Dec 31, 2025	32	255.56%	753,855	-74.34%	133	0.05%	29	314.29%	1	-50.00%
Sep 30, 2025	9	200.00%	2,937,895	43.53%	521	2575.15%	7	-	2	-
Jun 30, 2025	3	-89.29%	2,046,828	-73.79%	4	1.51%	-	-100.00%	-	-100.00%
Mar 31, 2025	30	-	10,436,800	-6.52%	23	3.25%	10	-9.09%	7	-30.00%
Dec 31, 2024	30	-6.25%	11,164,918	-17.90%	27	2.49%	11	37.50%	10	-9.09%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard Institutional Extnd Mkt Idx Tr	11.91K	2.11%	-
Vanguard Total Stock Mkt Idx Inv	638.56K	1.55%	-
Vanguard US Total Market Shares ETF	638.56K	1.55%	-
Fidelity Extended Market Index	5.72K	1.02%	5.72K
Blackrock Extended Mkt Fund CF	3.48K	0.62%	3.48K
Extended Equity Market Fund K	2.98K	0.53%	2.98K
Fidelity Total Market Index	1.92K	0.34%	1.92K
Spartan Extended Market Index Pool F	1.59K	0.28%	1.59K
NT Ext Equity Mkt Idx Fd - L	1.29K	0.23%	1.29K
Fidelity Series Total Market Index	1.21K	0.21%	1.21K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Buy	$4.59K
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Sell	$436.39
Oct 06, 2025	Parkman Healthcare Partners LLC	-	Sell	$4.48K
Mar 21, 2024	Novo Holdings A/S	-	Sell	$350.95K
Mar 19, 2024	Novo Holdings A/S	-	Sell	$447.71K

Insider Transactions Trends

Date	Buy	Sell
2026 Q1	-	-
2025 Q4	1	2
2025 Q3	-	-
2024 Q4	-	-
2024 Q2	-	-

SPRB Ownership FAQ

Who Owns Spruce Biosciences?

Spruce Biosciences shareholders are primarily institutional investors at 133.88%, followed by 9.12% insiders and -43.00% retail investors. The average institutional ownership in Spruce Biosciences's industry, Biotech Stocks , is 381.47%, which Spruce Biosciences falls below.

Who owns the most shares of Spruce Biosciences?

Spruce Biosciences’s largest shareholders are Rivervest venture management (2.94M shares, 7.14%), Rock springs capital management lp (2.61M shares, 6.32%), and Blackrock (124.73K shares, 0.30%). Together, they hold 13.77% of Spruce Biosciences’s total shares outstanding.

Does Blackrock own Spruce Biosciences?

Yes, BlackRock owns 0.30% of Spruce Biosciences, totaling 124.73K shares as of Jun 2024. This represents 0% of BlackRock's total assets, with a market value of 64.58K$. In the last quarter, BlackRock decreased its holdings by -61.214K shares, a -32.92% change.

Who is Spruce Biosciences’s biggest shareholder by percentage of total assets invested?

Rivervest venture management is Spruce Biosciences’s biggest shareholder by percentage of total assets invested, with 22.27% of its assets in 2.94M Spruce Biosciences shares, valued at 1.52M$.

Who is the top mutual fund holder of Spruce Biosciences shares?

Vanguard Institutional Extnd Mkt Idx Tr is the top mutual fund holder of Spruce Biosciences shares, with 2.11% of its total shares outstanding invested in 11.91K Spruce Biosciences shares.

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