Tyra Biosciences Ownership | Who Owns Tyra Biosciences?

Tyra Biosciences Ownership Summary

Tyra Biosciences is owned by 44.17% institutional investors, 3.15% insiders, and 52.68% retail investors. Ra capital management is the largest institutional shareholder, holding 20.47% of TYRA shares. Fidelity OTC is the top mutual fund, with 4.43% of its assets in Tyra Biosciences shares.

TYRA Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Tyra Biosciences	44.17%	3.15%	52.68%
Sector	Healthcare Stocks	232.80%	10.63%	-143.43%
Industry	Biotech Stocks	379.48%	10.37%	-289.85%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Ra capital management	12.20M	20.47%	$467.21M
Fmr	7.75M	13.00%	$296.73M
Boxer capital	6.45M	12.35%	$103.11M
Nextech invest	4.06M	6.89%	$56.38M
Nextech invest	4.06M	6.80%	$155.34M
Janus henderson group	3.89M	6.53%	$148.87M
Alta partners management	3.82M	6.41%	$146.44M
Farallon capital management	3.58M	6.01%	$137.15M
Tcg crossover management	3.25M	5.45%	$124.44M
Commodore capital lp	2.48M	4.15%	$94.79M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Alta partners management	3.82M	96.97%	$146.44M
Canaan partners xi	750.00K	37.76%	$28.73M
5am venture management	1.03M	10.94%	$39.42M
Nextech invest	4.06M	10.93%	$155.34M
Nextech invest	4.06M	9.15%	$56.38M
Commodore capital lp	2.48M	5.48%	$94.79M
Boxer capital	6.45M	5.43%	$103.11M
Ra capital management	12.20M	4.95%	$467.21M
Tcg crossover management	3.25M	3.56%	$124.44M
Sio capital management	605.44K	3.33%	$23.19M

Top Buyers

Holder	Shares	% Assets	Change
Fmr	7.75M	0.02%	7.74M
Paradigm biocapital advisors lp	2.05M	1.61%	2.05M
Farallon capital management	3.58M	0.78%	1.51M
Price t rowe associates inc /md/	986.06K	0.00%	971.63K
Janus henderson group	3.89M	0.07%	955.15K

Top Sellers

Holder	Shares	% Assets	Change
Canaan partners xi	750.00K	37.76%	-2.62M
Vestal point capital, lp	54.00K	0.06%	-2.37M
Kynam capital management, lp	-	-	-1.56M
Fairmount funds management	-	-	-1.39M
Commodore capital lp	2.48M	5.48%	-900.00K

New Positions

Holder	Shares	% Assets	Change	Value
Paradigm biocapital advisors lp	2.05M	1.61%	2.05M	$78.71M
Jennison associates	632.43K	0.02%	632.43K	$24.22M
Deerfield management company, l.p. (series c)	549.00K	0.25%	549.00K	$21.03M
Woodline partners lp	301.04K	0.04%	301.04K	$11.53M
Affinity asset advisors	257.51K	0.51%	257.51K	$9.86M

Sold Out

Holder	Change
Nelson, van denburg & campbell wealth management group	-2.00
Ifp advisors	-2.00
Srs capital advisors	-3.00
Capital performance advisors llp	-5.00
Corecap advisors	-16.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Dec 31, 2025	93	-19.83%	26,357,561	-52.63%	44	0.51%	49	-	28	-26.32%
Sep 30, 2025	115	-4.17%	55,638,535	-1.68%	93	1.03%	49	-40.24%	38	90.00%
Jun 30, 2025	119	1.71%	56,577,138	16.52%	95	1.42%	80	25.00%	21	-32.26%
Mar 31, 2025	118	4.42%	53,572,784	10.20%	90	1.32%	64	-8.57%	31	24.00%
Dec 31, 2024	110	11.11%	48,202,601	2.44%	81	1.28%	67	19.64%	25	25.00%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Fidelity OTC	2.63M	4.43%	2.63M
Vanguard Total Stock Mkt Idx Inv	836.17K	1.55%	-81.10K
Fidelity Small Cap Growth	800.38K	1.51%	-113.05K
State Street® SPDR® S&P® Biotech ETF	730.75K	1.23%	-7.22K
Fidelity Stock Selector Small Cap	598.94K	1.13%	-
Biotech Growth Ord	580.15K	1.09%	-
iShares Russell 2000 ETF	611.63K	1.03%	5.17K
Fidelity Series Small Cap Opps	508.83K	0.96%	-
Fidelity Advisor Equity Growth I	557.50K	0.94%	557.50K
Fidelity VIP Growth Initial	518.00K	0.87%	518.00K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Mar 25, 2026	KAPLAN GILLA	-	Sell	$528.51K
Feb 12, 2026	Bensen Daniel	Chief Discovery Officer	Sell	$195.93K
Feb 12, 2026	Bensen Daniel	Chief Discovery Officer	Sell	$67.04K
Jan 12, 2026	Bensen Daniel	Chief Discovery Officer	Sell	$198.61K
Jan 12, 2026	Bensen Daniel	Chief Discovery Officer	Sell	$29.58K

Insider Transactions Trends

Date	Buy	Sell
2026 Q2	-	-
2026 Q1	-	5
2025 Q4	-	9
2025 Q3	-	-
2025 Q2	6	5

TYRA Ownership FAQ

Who Owns Tyra Biosciences?

Tyra Biosciences shareholders are primarily institutional investors at 44.17%, followed by 3.15% insiders and 52.68% retail investors. The average institutional ownership in Tyra Biosciences's industry, Biotech Stocks , is 379.48%, which Tyra Biosciences falls below.

Who owns the most shares of Tyra Biosciences?

Tyra Biosciences’s largest shareholders are Ra capital management (12.2M shares, 20.47%), Fmr (7.75M shares, 13.00%), and Boxer capital (6.45M shares, 12.35%). Together, they hold 45.81% of Tyra Biosciences’s total shares outstanding.

Does Blackrock own Tyra Biosciences?

BlackRock is not among the top 10 institutional shareholders of Tyra Biosciences.

Who is Tyra Biosciences’s biggest shareholder by percentage of total assets invested?

Alta partners management is Tyra Biosciences’s biggest shareholder by percentage of total assets invested, with 96.97% of its assets in 3.82M Tyra Biosciences shares, valued at 146.44M$.

Who is the top mutual fund holder of Tyra Biosciences shares?

Fidelity OTC is the top mutual fund holder of Tyra Biosciences shares, with 4.43% of its total shares outstanding invested in 2.63M Tyra Biosciences shares.

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