Xenon Pharmaceuticals Ownership | Who Owns Xenon Pharmaceuticals?

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Xenon Pharmaceuticals Ownership Summary

Xenon Pharmaceuticals is owned by 12.77% institutional investors, 0.12% insiders, and 87.11% retail investors. Fmr is the largest institutional shareholder, holding 13.65% of XENE shares. American Funds SMALLCAP World A is the top mutual fund, with 3.67% of its assets in Xenon Pharmaceuticals shares.

XENE Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Xenon Pharmaceuticals	12.77%	0.12%	87.11%
Sector	Healthcare Stocks	35.58%	11.87%	52.55%
Industry	Biotech Stocks	35.75%	11.83%	52.41%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Fmr	10.82M	13.65%	$629.10M
Avoro capital advisors	5.78M	7.29%	$335.98M
Blackrock funding, inc. /de	5.64M	7.12%	$327.97M
Wellington management group llp	4.83M	6.09%	$280.84M
Driehaus capital management	4.49M	5.67%	$261.19M
Polar capital	4.41M	5.56%	$256.17M
Janus henderson group	4.18M	5.27%	$242.86M
Capital investors	2.67M	3.37%	$155.54M
Citadel advisors	2.65M	3.35%	$154.27M
Blackrock	2.10M	2.70%	$81.72M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Caligan partners lp	1.39M	5.39%	$81.00M
First turn management	786.84K	5.11%	$45.75M
Affinity asset advisors	1.68M	5.03%	$97.40M
Saturn v capital management	503.70K	4.44%	$20.22M
Tls advisors	30.96K	4.27%	$1.80M
Foresite capital management iv	160.00K	3.92%	$9.30M
Tri locum partners lp	366.10K	3.38%	$14.70M
Dafna capital management	250.77K	3.32%	$14.58M
Great point partners	200.00K	3.31%	$8.03M
Avoro capital advisors	5.78M	3.31%	$335.98M

Top Buyers

Holder	Shares	% Assets	Change
Polar capital	4.41M	0.91%	1.94M
Fmr	10.82M	0.03%	1.90M
Citadel advisors	2.65M	0.02%	1.33M
Alyeska investment group	1.30M	0.21%	1.30M
Deerfield management company, l.p. (series c)	1.62M	1.11%	1.07M

Top Sellers

Holder	Shares	% Assets	Change
Paradigm biocapital advisors lp	-	-	-2.04M
Samlyn capital	-	-	-1.02M
Commodore capital lp	825.00K	2.78%	-975.00K
Capital investors	2.67M	0.04%	-740.23K
Braidwell lp	1.34M	2.60%	-486.62K

New Positions

Holder	Shares	% Assets	Change	Value
Alyeska investment group	1.30M	0.21%	1.30M	$75.56M
Octagon capital advisors lp	490.00K	3.15%	490.00K	$28.49M
Novo	485.44K	2.29%	485.44K	$28.23M
Logos global management lp	450.00K	1.31%	450.00K	$26.17M
Tri locum partners lp	366.10K	3.38%	366.10K	$14.70M

Sold Out

Holder	Change
Dinuzzo private wealth	-2.00
Tortoise investment management	-2.00
Td private client wealth	-3.00
Sjs investment consulting	-5.00
American national bank	-5.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Mar 31, 2026	110	-57.85%	10,120,863	-88.02%	12	0.11%	74	-45.59%	20	-73.33%
Dec 31, 2025	150	-34.78%	31,012,004	-63.22%	39	0.34%	73	-31.13%	49	-30.00%
Sep 30, 2025	142	-30.39%	50,518,761	-37.12%	63	0.61%	62	-45.13%	48	-12.73%
Jun 30, 2025	211	0.48%	83,114,839	11.81%	105	1.18%	116	26.09%	57	-18.57%
Mar 31, 2025	213	-	76,727,655	0.58%	97	1.02%	92	-3.16%	72	5.88%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
American Funds SMALLCAP World A	3.50M	3.67%	-550.85K
Vanguard Health Care Inv	3.21M	3.33%	-127.83K
Strategic Advisers Fidelity US TtlStk	2.99M	3.10%	952.00K
Polar Capital Biotech S Inc	2.41M	2.49%	1.66M
iShares Russell 2000 ETF	2.03M	2.10%	17.11K
Polar Capital Healthcare Opports Inc	1.54M	1.60%	636.25K
Fidelity Select Health Care	1.20M	1.24%	-90.00K
Pictet Biotech	658.54K	0.87%	658.54K
Pictet-Biotech P USD	625.53K	0.81%	7.66K
Fidelity Small Cap Index	743.76K	0.77%	8.94K

Recent Insider Transactions

Date	Name	Role	Activity	Value
Jun 05, 2026	PATOU GARY	-	Sell	$70.25K
Jun 05, 2026	Cannon Gillian	-	Sell	$63.24K
Mar 13, 2026	KENNEY CHRISTOPHER JOHN	Chief Medical Officer	Sell	$77.87K
Mar 13, 2026	DiFabio Andrea	Chief Legal Officer	Sell	$74.11K
Mar 13, 2026	MORTIMER IAN	PRESIDENT & CEO	Sell	$403.58K

Insider Transactions Trends

Date	Buy	Sell
2026 Q2	-	-
2026 Q1	-	17
2025 Q4	-	5
2025 Q2	-	1
2025 Q1	-	4

XENE Ownership FAQ

Who Owns Xenon Pharmaceuticals?

Xenon Pharmaceuticals shareholders are primarily institutional investors at 12.77%, followed by 0.12% insiders and 87.11% retail investors. The average institutional ownership in Xenon Pharmaceuticals's industry, Biotech Stocks , is 35.75%, which Xenon Pharmaceuticals falls below.

Who owns the most shares of Xenon Pharmaceuticals?

Xenon Pharmaceuticals’s largest shareholders are Fmr (10.82M shares, 13.65%), Avoro capital advisors (5.78M shares, 7.29%), and Blackrock funding, inc. /de (5.64M shares, 7.12%). Together, they hold 28.06% of Xenon Pharmaceuticals’s total shares outstanding.

Does Blackrock own Xenon Pharmaceuticals?

Yes, BlackRock owns 2.70% of Xenon Pharmaceuticals, totaling 2.1M shares as of Jun 2024. This represents 0.00% of BlackRock's total assets, with a market value of 81.72M$. In the last quarter, BlackRock decreased its holdings by -26.034K shares, a -1.23% change.

Who is Xenon Pharmaceuticals’s biggest shareholder by percentage of total assets invested?

Caligan partners lp is Xenon Pharmaceuticals’s biggest shareholder by percentage of total assets invested, with 5.39% of its assets in 1.39M Xenon Pharmaceuticals shares, valued at 81M$.

Who is the top mutual fund holder of Xenon Pharmaceuticals shares?

American Funds SMALLCAP World A is the top mutual fund holder of Xenon Pharmaceuticals shares, with 3.67% of its total shares outstanding invested in 3.5M Xenon Pharmaceuticals shares.

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