Zymeworks (ZYME) Revenue & Revenue Breakdown


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Zymeworks Revenue Highlights


Latest Revenue (Y)

$-27.11M

Latest Revenue (Q)

$48.73M

Main Segment (Y)

Milestone Revenue

Zymeworks Revenue by Period


Zymeworks Revenue by Year

DateRevenueChange
2025-12-31$-27.11M-135.53%
2024-12-31$76.30M0.38%
2023-12-31$76.01M-81.57%
2022-12-31$412.48M1446.03%
2021-12-31$26.68M-31.50%
2020-12-31$38.95M31.84%
2019-12-31$29.54M-44.28%
2018-12-31$53.02M2.43%
2017-12-31$51.76M370.18%
2016-12-31$11.01M13.96%
2015-12-31$9.66M478.44%
2014-12-31$1.67M-

Zymeworks generated $-27.11M in revenue during NA 2025, up -135.53% compared to the previous quarter, and up -69.60% compared to the same period a year ago.

Zymeworks Revenue by Quarter

DateRevenueChange
2025-06-30$48.73M79.73%
2025-03-31$27.11M-12.64%
2024-12-31$31.03M93.94%
2024-09-30$16.00M-16.85%
2024-06-30$19.24M91.85%
2024-03-31$10.03M-40.74%
2023-12-31$16.93M2.54%
2023-09-30$16.51M135.73%
2023-06-30$7.00M-80.32%
2023-03-31$35.58M-91.16%
2022-12-31$402.49M15198.10%
2022-09-30$2.63M-51.65%
2022-06-30$5.44M184.03%
2022-03-31$1.92M-90.36%
2021-12-31$19.87M352.10%
2021-09-30$4.39M148.16%
2021-06-30$1.77M175.00%
2021-03-31$644.00K-95.89%
2020-12-31$15.68M493.27%
2020-09-30$2.64M-78.61%
2020-06-30$12.36M49.46%
2020-03-31$8.27M340.54%
2019-12-31$1.88M-76.12%
2019-09-30$7.86M-0.28%
2019-06-30$7.88M-33.90%
2019-03-31$11.93M-58.77%
2018-12-31$28.93M1308.23%
2018-09-30$2.05M-90.66%
2018-06-30$22.00M54900.00%
2018-03-31$40.00K-99.92%
2017-12-31$50.07M41976.47%
2017-09-30$119.00K-91.13%
2017-06-30$1.34M483.48%
2017-03-31$230.00K-89.70%
2016-12-31$2.23M2.76%
2016-09-30$2.17M-65.76%
2016-06-30$6.34M2320.99%
2016-03-31$262.00K-

Zymeworks generated $48.73M in revenue during Q2 2025, up 79.73% compared to the previous quarter, and up 485.80% compared to the same period a year ago.

Zymeworks Revenue Breakdown


Zymeworks Revenue Breakdown by Product

Annual Revenue by Product

Product/ServiceDec 25Dec 24Dec 23Dec 22
Royalty$2.48M$100.00K--
Option Exercise Fee$7.50M---
Research Support Payments And Other Service$5.62M$2.83M$52.62M$8.20M
Milestone Revenue$25.00M$25.00M--
Licensing Fee---$5.00M

Zymeworks's latest annual revenue breakdown by segment (product or service), as of Dec 25: Milestone Revenue (61.58%), Option Exercise Fee (18.47%), Research Support Payments And Other Service (13.83%), and Royalty (6.11%).

Quarterly Revenue by Product

Product/ServiceDec 25Sep 25Jun 25Mar 25Dec 24Sep 24Jun 24Mar 24Dec 23Sep 23Jun 23Mar 23Dec 22Sep 22
Upfront Fee$18.00M$18.00M$18.00M$18.00M----------
Milestone Revenue-$25.00M$20.00M$14.00M$2.50M$8.00M--------
Research Support Payments And Other Service-$352.00K$475.00K$4.49M$764.00K$1.11M$2.07M$10.04M$538.00K$1.16M----
Royalty-$831.00K$550.00K$202.00K----------
Deferred Revenue--$18.33M-----------
Option Exercise Fee--$7.50M-----------
License and Service------------$5.50M-
Milestone Payment------------$1.00M-
Other Product-------------$2.63M

Zymeworks's latest quarterly revenue breakdown by segment (product or service), as of Dec 25: Upfront Fee (100.00%).

Zymeworks Peer Comparison by Revenue


TickerCompanyLast Year RevenueLast Quarter Revenue
BCRXBioCryst Pharmaceuticals$874.84M$159.40M
ARDXArdelyx$407.32M$110.33M
MAZEMaze Therapeutics$167.50M-
WVEWave Life Sciences$42.73M$7.61M
IMNMImmunome$6.94M-
UPBUpstream Bio$2.37M$683.00K
NTLAIntellia Therapeutics-$13.78M
PHVSPharvaris--
SYRESpyre Therapeutics--
TRVITrevi Therapeutics--
ZYMEZymeworks$-27.11M$48.73M

ZYME Revenue FAQ


What is Zymeworks’s yearly revenue?

Zymeworks's yearly revenue for 2025 was $-27.11M, representing a decrease of -135.53% compared to 2024. The company's yearly revenue for 2024 was $76.3M, representing an increase of 0.38% compared to 2023. ZYME's yearly revenue for 2023 was $76.01M, representing a decrease of -81.57% compared to 2022.

What is Zymeworks’s quarterly revenue?

Zymeworks's quarterly revenue for Q2 2025 was $48.73M, a 79.73% increase from the previous quarter (Q1 2025), and a 153.21% increase year-over-year (Q2 2024). The company's quarterly revenue for Q1 2025 was $27.11M, a -12.64% decrease from the previous quarter (Q4 2024), and a 170.29% increase year-over-year (Q1 2024). ZYME's quarterly revenue for Q4 2024 was $31.03M, a 93.94% increase from the previous quarter (Q3 2024), and a 83.33% increase year-over-year (Q4 2023).

What is Zymeworks’s revenue growth rate?

Zymeworks's revenue growth rate for the last 3 years (2023-2025) was -135.67%, and for the last 5 years (2021-2025) was -201.61%.

What are Zymeworks’s revenue streams?

Zymeworks's revenue streams in c 25 are Royalty, Option Exercise Fee, Research Support Payments And Other Service, and Milestone Revenue. Royalty generated $2.48M in revenue, accounting 6.11% of the company's total revenue, up 2381.00% year-over-year. Option Exercise Fee generated $7.5M in revenue, accounting 18.47% of the company's total revenue Research Support Payments And Other Service generated $5.62M in revenue, accounting 13.83% of the company's total revenue, up 98.10% year-over-year. Milestone Revenue generated $25M in revenue, accounting 61.58% of the company's total revenue

What is Zymeworks’s main source of revenue?

For the fiscal year ending Dec 25, the largest source of revenue of Zymeworks was Milestone Revenue. This segment made a revenue of $25M, representing 61.58% of the company's total revenue.