Septerna Ownership | Who Owns Septerna?

Septerna Ownership Summary

Septerna is owned by 100.60% institutional investors, 6.74% insiders. Ra capital management is the largest institutional shareholder, holding 15.84% of SEPN shares.

SEPN Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Septerna	100.60%	6.74%	-7.34%
Sector	Healthcare Stocks	486.50%	11.08%	-397.59%
Industry	Biotech Stocks	304.14%	11.08%	-215.23%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Ra capital management	7.00M	15.84%	$73.95M
Trv gp v	6.22M	14.07%	$65.70M
Driehaus capital management	4.68M	10.60%	$49.47M
Bvf inc/il	4.40M	9.95%	$46.47M
Trv gp vi	4.21M	9.54%	$44.52M
Samsara biocapital	3.15M	7.13%	$33.29M
Siren	2.20M	4.99%	$23.28M
Blackrock funding, inc. /de	1.39M	3.15%	$14.70M
Avoro capital advisors	1.24M	2.80%	$13.08M
Checkpoint capital	824.88K	2.55%	$4.78M

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Trv gp vi	4.21M	69.32%	$44.52M
Trv gp v	6.22M	39.66%	$65.70M
Samsara biocapital	3.15M	6.81%	$33.29M
Checkpoint capital	824.88K	2.62%	$4.78M
Sio capital management	584.43K	2.36%	$6.18M
Bvf inc/il	4.40M	1.66%	$46.47M
Adar1 capital management	847.23K	1.37%	$8.96M
Ra capital management	7.00M	1.25%	$73.95M
Siren	2.20M	1.20%	$23.28M
Casdin capital	553.27K	0.53%	$5.85M

Top Buyers

Holder	Shares	% Assets	Change
Driehaus capital management	4.68M	0.40%	1.56M
Checkpoint capital	824.88K	2.62%	824.88K
Perceptive advisors	541.45K	0.21%	541.45K
Vr adviser	540.45K	0.43%	540.45K
Millennium management	436.56K	0.00%	436.56K

Top Sellers

Holder	Shares	% Assets	Change
Deep track capital, lp	121.72K	0.04%	-1.79M
Soleus capital management	75.46K	0.05%	-675.90K
Sio capital management	584.43K	2.36%	-204.24K
Avoro capital advisors	1.24M	0.23%	-100.00K
Stonepine capital management	-	-	-68.08K

New Positions

Holder	Shares	% Assets	Change	Value
Checkpoint capital	824.88K	2.62%	824.88K	$4.78M
Vr adviser	540.45K	0.43%	540.45K	$5.71M
Millennium management	436.56K	0.00%	436.56K	$2.53M
Boothbay fund management	24.14K	0.01%	24.14K	$255.18K
Tudor investment corp et al	16.76K	0.00%	16.76K	$177.16K

Sold Out

Holder	Change
Corebridge financial	-9.10K
Chicago partners investment group	-10.95K
Stoneridge investment partners	-18.48K
Swiss national bank	-30.10K
Stonepine capital management	-68.08K

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Jun 30, 2025	94	27.03%	44,430,374	-1.90%	100	0.95%	57	-19.72%	19	-
Mar 31, 2025	1	-	1,912,929	-	5	-	1	-	-	-

Insider Transactions Trends

Date	Buy	Sell
2025 Q3	-	-
2025 Q2	-	-

SEPN Ownership FAQ

Who Owns Septerna?

Septerna shareholders are primarily institutional investors at 100.60%, followed by 6.74% insiders and -7.34% retail investors. The average institutional ownership in Septerna's industry, Biotech Stocks , is 304.14%, which Septerna falls below.

Who owns the most shares of Septerna?

Septerna’s largest shareholders are Ra capital management (7M shares, 15.84%), Trv gp v (6.22M shares, 14.07%), and Driehaus capital management (4.68M shares, 10.60%). Together, they hold 40.51% of Septerna’s total shares outstanding.

Does Blackrock own Septerna?

BlackRock is not among the top 10 institutional shareholders of Septerna.

Who is Septerna’s biggest shareholder by percentage of total assets invested?

Trv gp vi is Septerna’s biggest shareholder by percentage of total assets invested, with 69.32% of its assets in 4.21M Septerna shares, valued at 44.52M$.

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