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Septerna (SEPN) Stock Forecast, Price Target & Predictions

OverviewRevenueOwnershipFinancialsChart

SEPN Stock Forecast

Septerna (SEPN) stock forecast, based on 8 Wall Street analysts, predicts a 12-month average price target of $50.25, with a high of $60.00 and a low of $43.00. This represents a 50.13% increase from the last price of $33.47.

SEPN Stock Rating

Septerna stock's rating consensus is Buy, based on 8 Wall Street analysts. The breakdown includes 1 Strong Buy (12.50%), 7 Buy (87.50%), 0 Hold (0.00%), 0 Sell (0.00%), and 0 Strong Sell (0.00%).

Buy
Total 8 0 7 1 Strong Sell Sell Hold Buy Strong Buy

SEPN Price Target Upside V Benchmarks

TypeNameUpside
StockSepterna50.13%
SectorHealthcare Stocks 15.45%
IndustryBiotech Stocks 41.48%

Price Target Trends

1M3M12M
# Anlaysts249
Avg Price Target$44.00$48.25$43.11
Last Closing Price$33.47$33.47$33.47
Upside/Downside31.46%44.16%28.80%
Ratings Trends
DateStrong BuyBuyHoldSellStrong SellTotal
Jul, 2619---10
Jun, 2618---9
May, 2617---8
Apr, 2617---8
Mar, 2617---8
Analyst Price Target Forecasts
DateAnalystCompanyPrice TargetPrice when PublishedPrice Target/Price when PublishedPrice Target/Last Closing Price
Jul 01, 2026Guggenheim$45.00$33.4934.37%34.45%
Jul 01, 2026Truist Financial$43.00$33.4928.40%28.47%
Jun 11, 2026Guggenheim$52.00$30.4770.66%55.36%
Jun 08, 2026Raymond James$53.00$31.1570.14%58.35%
Mar 10, 2026Josh SchimmerCantor Fitzgerald$60.00$28.06113.83%79.27%
Jan 20, 2026H.C. Wainwright$35.00$26.0734.25%4.57%
Dec 19, 2025Martin AusterRaymond James$38.00$27.5437.98%13.53%
Dec 15, 2025Truist Financial$34.00$25.4733.49%1.58%
Nov 14, 2025Derek ArchilaWells Fargo$28.00$19.2445.53%-16.34%
May 16, 2025Derek ArchilaWells Fargo$18.00$9.8482.93%-46.22%
Analyst Rating Forecasts
DateCompanyPrevious RatingNew RatingRating Change
Jul 01, 2026GuggenheimBuyBuyhold
Jun 11, 2026GuggenheimBuyinitialise
Jun 08, 2026Raymond JamesStrong BuyStrong Buyhold
Mar 10, 2026Cantor FitzgeraldOverweightOverweighthold
Jan 20, 2026H.C. WainwrightBuyBuyhold
Dec 19, 2025Raymond JamesStrong Buyinitialise
Nov 14, 2025Wells FargoOverweightupgrade

Financial Forecast

EPS Forecast

$-11 $-9 $-7 $-5 $-3 $-1 Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$-7.26$-1.10--
Avg Forecast$-7.11$-2.36$-2.30$-1.83
High Forecast$-5.19$-2.16$-1.45$-1.83
Low Forecast$-10.38$-2.58$-3.14$-1.83
Surprise %2.11%-53.39%--

Revenue Forecast

$0 $10M $20M $30M $40M $50M Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$1.07M$45.95M--
Avg Forecast$690.00K$350.00K$151.00K$16.67M
High Forecast$690.00K$350.00K$151.00K$16.67M
Low Forecast$690.00K$350.00K$151.00K$16.67M
Surprise %55.80%13028.86%--

Net Income Forecast

$-200M $-160M $-120M $-80M $-40M $0 Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$-71.80M$-48.88M--
Avg Forecast$-112.68M$-34.30M$-33.25M$-26.49M
High Forecast$-75.12M$-31.26M$-20.99M$-26.49M
Low Forecast$-150.24M$-37.34M$-45.52M$-26.49M
Surprise %-36.28%42.49%--

SEPN Forecast FAQ

Is Septerna stock a buy?

Septerna stock has a consensus rating of Buy, based on 8 Wall Street analysts. The rating breakdown includes 1 Strong Buy, 7 Buy, 0 Hold, 0 Sell, and 0 Strong Sell, reflecting a consensus that Septerna is a favorable investment for most analysts.

What is Septerna's price target?

Septerna's price target, set by 8 Wall Street analysts, averages $50.25 over the next 12 months. The price target range spans from $43 at the low end to $60 at the high end, suggesting a potential 50.13% change from the previous closing price of $33.47.

How does Septerna stock forecast compare to its benchmarks?

Septerna's stock forecast shows a 50.13% upside, outperforming the average forecast for the healthcare stocks sector (15.45%) and outperforming the biotech stocks industry (41.48%).

What is the breakdown of analyst ratings for Septerna over the past three months?

  • July 2026: 10.00% Strong Buy, 90.00% Buy, 0% Hold, 0% Sell, 0% Strong Sell.
  • June 2026: 11.11% Strong Buy, 88.89% Buy, 0% Hold, 0% Sell, 0% Strong Sell.
  • May 2026: 12.50% Strong Buy, 87.50% Buy, 0% Hold, 0% Sell, 0% Strong Sell.

What is Septerna’s EPS forecast?

Septerna's average annual EPS forecast for its fiscal year ending in December 2026 is $-2.3, marking a 109.09% increase from the reported $-1.1 in 2025. Estimates for the following years are.

What is Septerna’s revenue forecast?

Septerna's average annual revenue forecast for its fiscal year ending in December 2026 is $151K, reflecting a -99.67% decrease from the reported $45.95M in 2025. The forecast for.

What is Septerna’s net income forecast?

Septerna's net income forecast for the fiscal year ending in December 2026 stands at $-33.253M, representing a -31.97% decrease from the reported $-48.879M in 2025. Projections indicate .