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Septerna (SEPN) Stock Forecast, Price Target & Predictions

OverviewRevenueOwnershipFinancialsChart

SEPN Stock Forecast

Septerna (SEPN) stock forecast, based on 6 Wall Street analysts, predicts a 12-month average price target of $39.00, with a high of $60.00 and a low of $28.00. This represents a 56.06% increase from the last price of $24.99.

SEPN Stock Rating

Septerna stock's rating consensus is Buy, based on 6 Wall Street analysts. The breakdown includes 0 Strong Buy (0.00%), 6 Buy (100.00%), 0 Hold (0.00%), 0 Sell (0.00%), and 0 Strong Sell (0.00%).

Buy
Total 6 0 6 Strong Sell Sell Hold Buy Strong Buy

SEPN Price Target Upside V Benchmarks

TypeNameUpside
StockSepterna56.06%
SectorHealthcare Stocks 15.45%
IndustryBiotech Stocks 41.48%

Price Target Trends

1M3M12M
# Anlaysts-26
Avg Price Target-$47.50$35.50
Last Closing Price$24.99$24.99$24.99
Upside/Downside-90.08%42.06%
Ratings Trends
DateStrong BuyBuyHoldSellStrong SellTotal
Apr, 2617---8
Mar, 2617---8
Feb, 2617---8
Jan, 2617---8
Dec, 2514---5
Analyst Price Target Forecasts
DateAnalystCompanyPrice TargetPrice when PublishedPrice Target/Price when PublishedPrice Target/Last Closing Price
Mar 10, 2026Josh SchimmerCantor Fitzgerald$60.00$28.06113.83%140.10%
Jan 20, 2026H.C. Wainwright$35.00$26.0734.25%40.06%
Dec 19, 2025Martin AusterRaymond James$38.00$27.5437.98%52.06%
Dec 15, 2025Truist Financial$34.00$25.4733.49%36.05%
Nov 14, 2025Derek ArchilaWells Fargo$28.00$19.2445.53%12.04%
May 16, 2025Derek ArchilaWells Fargo$18.00$9.8482.93%-27.97%
Mar 28, 2025Wells Fargo$11.00$6.1080.33%-55.98%
Feb 18, 2025Derek ArchilaWells Fargo$14.00$12.968.02%-43.98%
Analyst Rating Forecasts
DateCompanyPrevious RatingNew RatingRating Change
Mar 10, 2026Cantor FitzgeraldOverweightOverweighthold
Jan 20, 2026H.C. WainwrightBuyBuyhold
Dec 19, 2025Raymond JamesStrong Buyinitialise
Nov 14, 2025Wells FargoOverweightupgrade

Financial Forecast

EPS Forecast

$-11 $-9 $-7 $-5 $-3 $-1 Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$-7.26$-1.10--
Avg Forecast$-7.11$-2.36$-2.30$-1.83
High Forecast$-5.19$-2.16$-1.45$-1.83
Low Forecast$-10.38$-2.58$-3.14$-1.83
Surprise %2.11%-53.39%--

Revenue Forecast

$0 $10M $20M $30M $40M $50M Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$1.07M$45.95M--
Avg Forecast$690.00K$350.00K$151.00K$16.67M
High Forecast$690.00K$350.00K$151.00K$16.67M
Low Forecast$690.00K$350.00K$151.00K$16.67M
Surprise %55.80%13028.86%--

Net Income Forecast

$-200M $-160M $-120M $-80M $-40M $0 Dec 24 Dec 25 Dec 26 Dec 27
Dec 24Dec 25Dec 26Dec 27
Reported$-71.80M$-48.88M--
Avg Forecast$-112.68M$-34.30M$-33.25M$-26.49M
High Forecast$-75.12M$-31.26M$-20.99M$-26.49M
Low Forecast$-150.24M$-37.34M$-45.52M$-26.49M
Surprise %-36.28%42.49%--

SEPN Forecast FAQ

Is Septerna stock a buy?

Septerna stock has a consensus rating of Buy, based on 6 Wall Street analysts. The rating breakdown includes 0 Strong Buy, 6 Buy, 0 Hold, 0 Sell, and 0 Strong Sell, reflecting a consensus that Septerna is a favorable investment for most analysts.

What is Septerna's price target?

Septerna's price target, set by 6 Wall Street analysts, averages $39 over the next 12 months. The price target range spans from $28 at the low end to $60 at the high end, suggesting a potential 56.06% change from the previous closing price of $24.99.

How does Septerna stock forecast compare to its benchmarks?

Septerna's stock forecast shows a 56.06% upside, outperforming the average forecast for the healthcare stocks sector (15.45%) and outperforming the biotech stocks industry (41.48%).

What is the breakdown of analyst ratings for Septerna over the past three months?

  • April 2026: 12.50% Strong Buy, 87.50% Buy, 0% Hold, 0% Sell, 0% Strong Sell.
  • March 2026: 12.50% Strong Buy, 87.50% Buy, 0% Hold, 0% Sell, 0% Strong Sell.
  • February 2026: 12.50% Strong Buy, 87.50% Buy, 0% Hold, 0% Sell, 0% Strong Sell.

What is Septerna’s EPS forecast?

Septerna's average annual EPS forecast for its fiscal year ending in December 2026 is $-2.3, marking a 109.09% increase from the reported $-1.1 in 2025. Estimates for the following years are.

What is Septerna’s revenue forecast?

Septerna's average annual revenue forecast for its fiscal year ending in December 2026 is $151K, reflecting a -99.67% decrease from the reported $45.95M in 2025. The forecast for.

What is Septerna’s net income forecast?

Septerna's net income forecast for the fiscal year ending in December 2026 stands at $-33.253M, representing a -31.97% decrease from the reported $-48.879M in 2025. Projections indicate .