Spero Therapeutics Ownership | Who Owns Spero Therapeutics?
Spero Therapeutics Ownership Summary
Spero Therapeutics is owned by 37.06% institutional investors, 22.61% insiders, and 40.33% retail investors. Gsk is the largest institutional shareholder, holding 16.41% of SPRO shares. Vanguard Morn Total Stk Mkt Idx Investor is the top mutual fund, with 2.41% of its assets in Spero Therapeutics shares.
SPRO Ownership Benchmark
| Type | Name | % Inst | % Insiders | % Retail |
|---|---|---|---|---|
| Stock | Spero Therapeutics | 37.06% | 22.61% | 40.33% |
| Sector | Healthcare Stocks | 244.59% | 12.11% | -156.70% |
| Industry | Biotech Stocks | 379.61% | 11.70% | -291.31% |
Institutional Shareholders
Top Institutional Shareholders by Total Shares
| Holder | Shares | % Holding | Value |
|---|---|---|---|
| Gsk | 9.19M | 16.41% | $21.51M |
| Pfizer | 2.36M | 4.22% | $5.50M |
| Vanguard group | 2.08M | 3.70% | $4.85M |
| Renaissance | 1.19M | 2.12% | $2.78M |
| Alphabet | 889.98K | 1.59% | $2.08M |
| Two sigma investments, lp | 885.63K | 1.58% | $2.07M |
| Geode capital management | 519.92K | 0.93% | $1.22M |
| Blackrock | 483.40K | 0.90% | $628.42K |
| Blackrock funding, inc. /de | 433.20K | 0.77% | $1.01M |
| Citadel advisors | 376.46K | 0.67% | $880.91K |
Top Institutional Shareholders by % of Total Assets
| Holder | Shares | % Assets | Value |
|---|---|---|---|
| Gsk | 9.19M | 3.59% | $21.51M |
| Pfizer | 2.36M | 2.31% | $5.50M |
| Verdad advisers, lp | 33.45K | 0.09% | $78.28K |
| Awm investment company | 333.40K | 0.06% | $433.42K |
| Alphabet | 889.98K | 0.05% | $2.08M |
| Rangeley capital | 30.00K | 0.05% | $56.40K |
| Gsa capital partners llp | 278.30K | 0.04% | $651.00K |
| Ionic capital management | 195.94K | 0.03% | $458.50K |
| Three seasons wealth | 30.00K | 0.03% | $70.20K |
| Adar1 capital management | 115.54K | 0.02% | $217.21K |
Top Buyers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Two sigma investments, lp | 885.63K | 0.00% | 513.06K |
| Vanguard fiduciary trust | 264.12K | 0.00% | 264.12K |
| Gsa capital partners llp | 278.30K | 0.04% | 99.37K |
| Vanguard group | 2.08M | 0.00% | 93.61K |
| Susquehanna group, llp | 333.12K | 0.00% | 39.41K |
Top Sellers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Murchinson | - | - | -873.91K |
| Novo | - | - | -468.90K |
| Anson funds management lp | - | - | -421.96K |
| Monimus capital management, lp | - | - | -310.91K |
| Atlas venture life science advisors | - | - | -305.25K |
New Positions
| Holder | Shares | % Assets | Change | Value |
|---|---|---|---|---|
| Vanguard fiduciary trust | 264.12K | 0.00% | 264.12K | $618.03K |
| Verdad advisers, lp | 33.45K | 0.09% | 33.45K | $78.28K |
| Rangeley capital | 30.00K | 0.05% | 30.00K | $56.40K |
| Vanguard global advisers | 25.45K | - | 25.45K | $59.54K |
Sold Out
| Holder | Change |
|---|---|
| Qube research | -1.00 |
| Caitong asset management | -3.00 |
| Federation des caisses desjardins du quebec | -30.00 |
| Bnp paribas arbitrage, snc | -40.00 |
| Northwestern mutual wealth management | -50.00 |
Institutional Ownership Trends
| Date | Holdings | Change % | Shares | Change % | Ownership | Change % | Increased Position | Change % | Decreased Position | Change % |
|---|---|---|---|---|---|---|---|---|---|---|
| Jun 30, 2026 | 66 | 20.00% | 21,482,335 | 4.06% | 37 | 2.85% | 39 | 95.00% | 7 | -36.36% |
| Mar 31, 2026 | 30 | -48.28% | 17,313,997 | -18.02% | 30 | 2.19% | 8 | -72.41% | 6 | -53.85% |
| Dec 31, 2025 | 10 | -79.59% | 2,465,493 | -78.20% | 4 | 1.07% | 4 | -85.19% | 2 | -71.43% |
| Sep 30, 2025 | 11 | -74.42% | 3,157,628 | -71.20% | 5 | 1.47% | 3 | -86.96% | 1 | -88.89% |
| Jun 30, 2025 | 45 | 9.76% | 11,078,414 | -26.67% | 19 | 2.66% | 24 | 118.18% | 9 | -10.00% |
Top Mutual Funds Shareholders
| Holder | Shares | % Holding | Change |
|---|---|---|---|
| Vanguard Morn Total Stk Mkt Idx Investor | 1.40M | 2.41% | 159.20K |
| Vanguard Total Stock Mkt Idx Inv | 1.40M | 2.41% | 159.20K |
| Vanguard MStar Total Stk Mkt Idx Invest | 1.40M | 2.40% | - |
| Vanguard US Total Market Shares ETF | 1.17M | 2.09% | - |
| Vanguard Institutional Extnd Mkt Idx Tr | 593.25K | 1.02% | - |
| Acuitas US Microcap Strategy | 462.19K | 0.79% | 462.19K |
| IMC US Ultra Micro Cap | 264.02K | 0.47% | - |
| Fidelity Extended Market Index | 249.43K | 0.43% | 25.36K |
| iShares Micro-Cap ETF | 149.21K | 0.26% | -1.99K |
| Pleiades Small Cap Equity A | 132.01K | 0.23% | -38.96K |
Recent Insider Transactions
| Date | Name | Role | Activity | Value |
|---|---|---|---|---|
| May 04, 2026 | Rajavelu Esther | See Remarks | Sell | $63.35K |
| Feb 06, 2026 | Rajavelu Esther | See Remarks | Sell | $119.93K |
| Feb 06, 2026 | Rajavelu Esther | See Remarks | Sell | $87.56K |
| Feb 06, 2026 | Keutzer Timothy | Chief Operating Officer | Sell | $44.02K |
| Feb 03, 2026 | Keutzer Timothy | Chief Operating Officer | Sell | $51.84K |
Insider Transactions Trends
| Date | Buy | Sell |
|---|---|---|
| 2026 Q2 | - | 1 |
| 2026 Q1 | - | 7 |
| 2025 Q4 | - | 1 |
| 2025 Q3 | - | 2 |
| 2025 Q2 | - | - |
SPRO Ownership FAQ
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