Spero Therapeutics Ownership | Who Owns Spero Therapeutics?

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Spero Therapeutics Ownership Summary

Spero Therapeutics is owned by 19.77% institutional investors, 24.45% insiders, and 55.78% retail investors. Pfizer is the largest institutional shareholder, holding 4.22% of SPRO shares. Vanguard US Total Market Shares ETF is the top mutual fund, with 2.09% of its assets in Spero Therapeutics shares.

SPRO Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Spero Therapeutics	19.77%	24.45%	55.78%
Sector	Healthcare Stocks	488.17%	11.08%	-399.26%
Industry	Biotech Stocks	306.59%	11.10%	-217.69%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Pfizer	2.36M	4.22%	$6.85M
Vanguard group	1.76M	3.26%	$1.82M
Anson funds management lp	1.62M	2.88%	$4.68M
Renaissance	1.11M	2.04%	$1.14M
Alphabet	889.98K	1.59%	$2.58M
Blackrock	483.40K	0.90%	$628.42K
Geode capital management	481.13K	0.89%	$495.70K
Blackrock funding, inc. /de	434.77K	0.78%	$1.26M
Awm investment company	333.40K	0.62%	$433.42K
Bridgeway capital management	184.80K	0.34%	$190.34K

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Pfizer	2.36M	1.19%	$6.85M
Anson funds management lp	1.62M	0.67%	$4.68M
Stonepine capital management	156.89K	0.45%	$454.98K
Ionic capital management	150.00K	0.12%	$435.00K
Alphabet	889.98K	0.12%	$2.58M
Adar1 capital management	143.92K	0.06%	$417.36K
Awm investment company	333.40K	0.06%	$433.42K
Capital asset advisory services	32.55K	0.00%	$94.39K
Bridgeway capital management	184.80K	0.00%	$190.34K
Xtx topco	34.55K	0.00%	$100.20K

Top Buyers

Holder	Shares	% Assets	Change
Stonepine capital management	156.89K	0.45%	156.89K
Ionic capital management	150.00K	0.12%	150.00K
Renaissance	1.11M	0.00%	130.94K
Jpmorgan chase	61.62K	-	61.39K
Xtx topco	34.55K	0.00%	34.55K

Top Sellers

Holder	Shares	% Assets	Change
Anson funds management lp	1.62M	0.67%	-2.18M
Murchinson	-	-	-873.91K
Acadian asset management	112.89K	0.00%	-758.32K
Adar1 capital management	143.92K	0.06%	-657.36K
Novo	-	-	-468.90K

New Positions

Holder	Shares	% Assets	Change	Value
Stonepine capital management	156.89K	0.45%	156.89K	$454.98K
Ionic capital management	150.00K	0.12%	150.00K	$435.00K
Capital asset advisory services	32.55K	0.00%	32.55K	$94.39K
Quadrature capital	31.20K	0.00%	31.20K	$90.50K
Raymond james financial	3.08K	-	3.08K	$8.94K

Sold Out

Holder	Change
Qube research	-1.00
Federation des caisses desjardins du quebec	-30.00
Pfs partners	-50.00
Northwestern mutual wealth management	-50.00
Corecap advisors	-50.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Jun 30, 2025	45	9.76%	11,078,414	-26.67%	19	2.66%	24	118.18%	9	-10.00%
Mar 31, 2025	4	-92.31%	2,111,095	-86.54%	3	0.47%	-	-100.00%	-	-100.00%
Dec 31, 2024	52	10.64%	15,679,985	27.34%	28	5.60%	26	160.00%	9	-25.00%
Sep 30, 2024	47	-4.08%	12,313,754	-11.17%	22	3.39%	10	-41.18%	12	50.00%
Jun 30, 2024	49	-9.26%	13,861,979	0.87%	25	3.81%	17	-29.17%	8	-33.33%

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard US Total Market Shares ETF	1.17M	2.09%	-
Vanguard Total Stock Mkt Idx Inv	1.14M	2.03%	-25.17K
Vanguard Institutional Extnd Mkt Idx Tr	516.11K	0.92%	-235.18K
IMC US Ultra Micro Cap	255.33K	0.45%	-
Fidelity Extended Market Index	237.49K	0.42%	-620.00
Pleiades Small Cap Equity A	127.66K	0.23%	127.66K
Fidelity Total Market Index	108.99K	0.19%	-
Extended Equity Market Fund K	107.09K	0.19%	47.16K
iShares Micro-Cap ETF	87.05K	0.16%	-
Mackenzie US Small Cap A	65.79K	0.12%	-

Recent Insider Transactions

Date	Name	Role	Activity	Value
Aug 28, 2025	Mahadevia Ankit	-	Sell	$12.95K
Aug 28, 2025	Keutzer Timothy	Chief Operating Officer	Sell	$3.34K
Feb 05, 2025	Keutzer Timothy	Chief Operating Officer	Sell	$21.56K
Feb 05, 2025	Keutzer Timothy	Chief Operating Officer	Sell	$3.10K
Feb 05, 2025	Keutzer Timothy	Chief Operating Officer	Sell	$19.44K

Insider Transactions Trends

Date	Buy	Sell
2025 Q1	-	9
2024 Q4	-	2
2024 Q3	-	5
2024 Q2	-	-
2024 Q1	-	6

SPRO Ownership FAQ

Who Owns Spero Therapeutics?

Spero Therapeutics shareholders are primarily institutional investors at 19.77%, followed by 24.45% insiders and 55.78% retail investors. The average institutional ownership in Spero Therapeutics's industry, Biotech Stocks , is 306.59%, which Spero Therapeutics falls below.

Who owns the most shares of Spero Therapeutics?

Spero Therapeutics’s largest shareholders are Pfizer (2.36M shares, 4.22%), Vanguard group (1.76M shares, 3.26%), and Anson funds management lp (1.62M shares, 2.88%). Together, they hold 10.36% of Spero Therapeutics’s total shares outstanding.

Does Blackrock own Spero Therapeutics?

Yes, BlackRock owns 0.90% of Spero Therapeutics, totaling 483.4K shares as of Jun 2024. This represents 0% of BlackRock's total assets, with a market value of 628.42K$. In the last quarter, BlackRock increased its holdings by 6.51K shares, a 1.36% change.

Who is Spero Therapeutics’s biggest shareholder by percentage of total assets invested?

Pfizer is Spero Therapeutics’s biggest shareholder by percentage of total assets invested, with 1.19% of its assets in 2.36M Spero Therapeutics shares, valued at 6.85M$.

Who is the top mutual fund holder of Spero Therapeutics shares?

Vanguard US Total Market Shares ETF is the top mutual fund holder of Spero Therapeutics shares, with 2.09% of its total shares outstanding invested in 1.17M Spero Therapeutics shares.

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