Spero Therapeutics Ownership | Who Owns Spero Therapeutics?
Spero Therapeutics Ownership Summary
Spero Therapeutics is owned by 30.91% institutional investors, 22.52% insiders, and 46.58% retail investors. Gsk is the largest institutional shareholder, holding 16.41% of SPRO shares. Vanguard Total Stock Mkt Idx Inv is the top mutual fund, with 2.14% of its assets in Spero Therapeutics shares.
SPRO Ownership Benchmark
| Type | Name | % Inst | % Insiders | % Retail |
|---|---|---|---|---|
| Stock | Spero Therapeutics | 30.91% | 22.52% | 46.58% |
| Sector | Healthcare Stocks | 35.58% | 11.87% | 52.55% |
| Industry | Biotech Stocks | 35.75% | 11.83% | 52.41% |
Institutional Shareholders
Top Institutional Shareholders by Total Shares
| Holder | Shares | % Holding | Value |
|---|---|---|---|
| Gsk | 9.19M | 16.41% | $21.51M |
| Pfizer | 2.36M | 4.22% | $5.50M |
| Vanguard group | 2.08M | 3.70% | $4.85M |
| Renaissance | 1.19M | 2.12% | $2.78M |
| Alphabet | 889.98K | 1.59% | $2.08M |
| Two sigma investments, lp | 885.63K | 1.58% | $2.07M |
| Geode capital management | 519.92K | 0.93% | $1.22M |
| Blackrock | 483.40K | 0.90% | $628.42K |
| Blackrock funding, inc. /de | 433.20K | 0.77% | $1.01M |
| Anson funds management lp | 421.96K | 0.75% | $987.38K |
Top Institutional Shareholders by % of Total Assets
| Holder | Shares | % Assets | Value |
|---|---|---|---|
| Gsk | 9.19M | 3.59% | $21.51M |
| Pfizer | 2.36M | 2.31% | $5.50M |
| Verdad advisers, lp | 33.45K | 0.09% | $78.28K |
| Anson funds management lp | 421.96K | 0.09% | $987.38K |
| Awm investment company | 333.40K | 0.06% | $433.42K |
| Alphabet | 889.98K | 0.05% | $2.08M |
| Rangeley capital | 30.00K | 0.05% | $56.40K |
| Gsa capital partners llp | 278.30K | 0.04% | $651.00K |
| Ionic capital management | 195.94K | 0.03% | $458.50K |
| Intrepid family office | 16.28K | 0.03% | $38.09K |
Top Buyers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Two sigma investments, lp | 885.63K | 0.00% | 513.06K |
| Vanguard fiduciary trust | 264.12K | 0.00% | 264.12K |
| Marshall wace, llp | 157.07K | 0.00% | 157.07K |
| Gsa capital partners llp | 278.30K | 0.04% | 99.37K |
| Vanguard group | 2.08M | 0.00% | 93.61K |
Top Sellers
| Holder | Shares | % Assets | Change |
|---|---|---|---|
| Murchinson | - | - | -873.91K |
| Novo | - | - | -468.90K |
| Monimus capital management, lp | - | - | -310.91K |
| Atlas venture life science advisors | - | - | -305.25K |
| Eam investors | - | - | -218.08K |
New Positions
| Holder | Shares | % Assets | Change | Value |
|---|---|---|---|---|
| Vanguard fiduciary trust | 264.12K | 0.00% | 264.12K | $618.03K |
| Marshall wace, llp | 157.07K | 0.00% | 157.07K | $367.55K |
| Verdad advisers, lp | 33.45K | 0.09% | 33.45K | $78.28K |
| Rangeley capital | 30.00K | 0.05% | 30.00K | $56.40K |
| Vanguard global advisers | 25.45K | - | 25.45K | $59.54K |
Sold Out
| Holder | Change |
|---|---|
| Qube research | -1.00 |
| Federation des caisses desjardins du quebec | -30.00 |
| Northwestern mutual wealth management | -50.00 |
| Pfs partners | -50.00 |
| Corecap advisors | -50.00 |
Institutional Ownership Trends
| Date | Holdings | Change % | Shares | Change % | Ownership | Change % | Increased Position | Change % | Decreased Position | Change % |
|---|---|---|---|---|---|---|---|---|---|---|
| Mar 31, 2026 | 30 | -48.28% | 17,313,997 | -18.02% | 30 | 2.19% | 8 | -72.41% | 6 | -53.85% |
| Dec 31, 2025 | 10 | -79.59% | 2,465,493 | -78.20% | 4 | 1.07% | 4 | -85.19% | 2 | -71.43% |
| Sep 30, 2025 | 11 | -74.42% | 3,157,628 | -71.20% | 5 | 1.47% | 3 | -86.96% | 1 | -88.89% |
| Jun 30, 2025 | 45 | 9.76% | 11,078,414 | -26.67% | 19 | 2.66% | 24 | 118.18% | 9 | -10.00% |
| Mar 31, 2025 | 4 | -92.31% | 2,111,095 | -86.54% | 3 | 0.47% | - | -100.00% | - | -100.00% |
Top Mutual Funds Shareholders
| Holder | Shares | % Holding | Change |
|---|---|---|---|
| Vanguard Total Stock Mkt Idx Inv | 1.24M | 2.14% | - |
| Vanguard US Total Market Shares ETF | 1.17M | 2.09% | - |
| Vanguard Institutional Extnd Mkt Idx Tr | 516.11K | 0.89% | - |
| IMC US Ultra Micro Cap | 264.02K | 0.47% | - |
| Fidelity Extended Market Index | 206.60K | 0.36% | -902.00 |
| Pleiades Small Cap Equity A | 132.01K | 0.23% | -38.96K |
| Extended Equity Market Fund E | 126.66K | 0.22% | - |
| Blackrock Extended Mkt Fund CF | 126.66K | 0.22% | - |
| Extended Equity Market Fund B | 126.66K | 0.22% | - |
| Extended Equity Market Fund K | 107.85K | 0.19% | -790.00 |
Recent Insider Transactions
| Date | Name | Role | Activity | Value |
|---|---|---|---|---|
| May 04, 2026 | Rajavelu Esther | See Remarks | Sell | $63.35K |
| Feb 06, 2026 | Rajavelu Esther | See Remarks | Sell | $119.93K |
| Feb 06, 2026 | Rajavelu Esther | See Remarks | Sell | $87.56K |
| Feb 06, 2026 | Keutzer Timothy | Chief Operating Officer | Sell | $44.02K |
| Feb 03, 2026 | Keutzer Timothy | Chief Operating Officer | Sell | $51.84K |
Insider Transactions Trends
| Date | Buy | Sell |
|---|---|---|
| 2026 Q1 | - | 4 |
| 2025 Q4 | - | 1 |
| 2025 Q3 | - | 2 |
| 2025 Q2 | - | - |
| 2025 Q1 | - | 9 |
SPRO Ownership FAQ
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