Xilio Therapeutics Ownership | Who Owns Xilio Therapeutics?

Xilio Therapeutics Ownership Summary

Xilio Therapeutics is owned by 14.06% institutional investors, 35.34% insiders, and 50.60% retail investors. Gilead sciences is the largest institutional shareholder, holding 6.32% of XLO shares. Vanguard Institutional Extnd Mkt Idx Tr is the top mutual fund, with 1.02% of its assets in Xilio Therapeutics shares.

XLO Ownership Benchmark

Type	Name	% Inst	% Insiders	% Retail
Stock	Xilio Therapeutics	14.06%	35.34%	50.60%
Sector	Healthcare Stocks	232.86%	10.65%	-143.51%
Industry	Biotech Stocks	382.13%	10.41%	-292.54%

Institutional Shareholders

Top Institutional Shareholders by Total Shares

Holder	Shares	% Holding	Value
Gilead sciences	9.11M	6.32%	$5.83M
Rivervest venture management	1.44M	5.16%	$1.37M
Bain capital life sciences investors	4.57M	4.74%	$3.85M
Merck	1.48M	1.54%	$1.25M
Takeda pharmaceutical	1.48M	1.53%	$1.24M
Vanguard group	1.26M	0.87%	$803.64K
Empery asset management, lp	1.18M	0.82%	$757.38M
Morgan stanley	839.85K	0.58%	$537.67K
Fmr	511.82K	0.53%	$431.31K
Aju ib investment	667.74K	0.46%	$427.49K

Top Institutional Shareholders by % of Total Assets

Holder	Shares	% Assets	Value
Rivervest venture management	1.44M	20.01%	$1.37M
Takeda pharmaceutical	1.48M	7.59%	$1.24M
Aju ib investment	667.74K	1.88%	$427.49K
Empery asset management, lp	1.18M	0.67%	$757.38M
Merck	1.48M	0.55%	$1.25M
Gilead sciences	9.11M	0.30%	$5.83M
Bain capital life sciences investors	4.57M	0.26%	$3.85M
Gsa capital partners llp	147.97K	0.01%	$95.00K
Two sigma securities	32.13K	0.00%	$27.08K
Xtx topco	76.05K	0.00%	$64.08K

Top Buyers

Holder	Shares	% Assets	Change
Empery asset management, lp	1.18M	0.67%	1.18M
Gsa capital partners llp	147.97K	0.01%	147.97K
Renaissance	344.42K	0.00%	139.72K
State street	163.89K	-	120.50K
Susquehanna group, llp	49.09K	-	49.09K

Top Sellers

Holder	Shares	% Assets	Change
Rock springs capital management lp	-	-	-3.00M
Ghisallo capital management	-	-	-1.33M
Atlas venture life science advisors	-	-	-992.91K
Squarepoint ops	-	-	-328.79K
Trustees of columbia university in the city of new york	-	-	-249.63K

New Positions

Holder	Shares	% Assets	Change	Value
Empery asset management, lp	1.18M	0.67%	1.18M	$757.38M
Gsa capital partners llp	147.97K	0.01%	147.97K	$95.00K
Susquehanna group, llp	49.09K	-	49.09K	$46.88K
Jane street group	42.08K	-	42.08K	$26.94K
Raymond james & associates	38.83K	-	38.83K	$36.79K

Sold Out

Holder	Change
Qube research	-4.00
Jpmorgan chase	-62.00
Wells fargo & company/mn	-108.00
Citigroup	-258.00
Private wealth management group	-310.00

Institutional Ownership Trends

Date	Holdings	Change %	Shares	Change %	Ownership	Change %	Increased Position	Change %	Decreased Position	Change %
Dec 31, 2025	22	-38.89%	20,254,500	-8.15%	14	2.69%	8	-27.27%	3	-
Sep 30, 2025	36	5.88%	22,051,916	-1.34%	22	2.55%	11	10.00%	3	-72.73%
Jun 30, 2025	34	3.03%	23,770,263	21.47%	31	4.64%	11	-21.43%	10	42.86%
Mar 31, 2025	35	-	22,528,206	-12.87%	30	1.82%	14	-6.67%	7	16.67%
Dec 31, 2024	17	-48.48%	13,981,677	-12.36%	22	3.49%	5	-64.29%	4	-

Top Mutual Funds Shareholders

Holder	Shares	% Holding	Change
Vanguard Institutional Extnd Mkt Idx Tr	58.91K	1.02%	-308.92K
Vanguard Total Stock Mkt Idx Inv	51.70K	0.89%	-672.05K
Vanguard Instl Ttl Stk Mkt Idx InstlPls	13.05K	0.23%	13.05K
Fidelity Extended Market Index	141.90K	0.18%	-515.00
iShares Micro-Cap ETF	59.99K	0.12%	-
Fidelity Total Market Index	63.21K	0.08%	-
Bridgeway Ultra-Small Company Market	56.08K	0.08%	-
Fidelity Series Total Market Index	49.58K	0.06%	-
Spartan Extended Market Index Pool E	30.66K	0.06%	1.54K
Spartan Extended Market Index Pool F	37.89K	0.05%	-

Recent Insider Transactions

Date	Name	Role	Activity	Value
Mar 26, 2026	Shannon James Samuel	-	Buy	$43.95K
Feb 13, 2026	GILEAD SCIENCES, INC.	-	Buy	$373.90
Jan 02, 2026	Brennan Kevin M.	SVP, FINANCE AND ACCOUNTING	Sell	$1.17K
Jan 02, 2026	Frankenfield Christopher James	Chief Financial Officer	Sell	$4.52K
Jun 17, 2025	Shannon James Samuel	-	Buy	$17.21K

Insider Transactions Trends

Date	Buy	Sell
2026 Q2	-	-
2026 Q1	2	2
2025 Q4	-	-
2025 Q2	7	-
2025 Q1	-	2

XLO Ownership FAQ

Who Owns Xilio Therapeutics?

Xilio Therapeutics shareholders are primarily institutional investors at 14.06%, followed by 35.34% insiders and 50.60% retail investors. The average institutional ownership in Xilio Therapeutics's industry, Biotech Stocks , is 382.13%, which Xilio Therapeutics falls below.

Who owns the most shares of Xilio Therapeutics?

Xilio Therapeutics’s largest shareholders are Gilead sciences (9.11M shares, 6.32%), Rivervest venture management (1.44M shares, 5.16%), and Bain capital life sciences investors (4.57M shares, 4.74%). Together, they hold 16.22% of Xilio Therapeutics’s total shares outstanding.

Does Blackrock own Xilio Therapeutics?

BlackRock is not among the top 10 institutional shareholders of Xilio Therapeutics.

Who is Xilio Therapeutics’s biggest shareholder by percentage of total assets invested?

Rivervest venture management is Xilio Therapeutics’s biggest shareholder by percentage of total assets invested, with 20.01% of its assets in 1.44M Xilio Therapeutics shares, valued at 1.37M$.

Who is the top mutual fund holder of Xilio Therapeutics shares?

Vanguard Institutional Extnd Mkt Idx Tr is the top mutual fund holder of Xilio Therapeutics shares, with 1.02% of its total shares outstanding invested in 58.91K Xilio Therapeutics shares.

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